Further results comparing power across rare variant approaches.

<p>Results in Figures A and B show the effect of having both deleterious and protective rare variants. Figures C and D switches to a continuous trait, with Figure D showing the effect of having both deleterious and protective rare variants. Results are sorted by the plot that has the highest area, i.e., the most powerful overall. See the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013584#pone-0013584-g002" target="_blank">Figure 2</a> legend for additional details about the different simulations.