Evaluation of AAV8.TBG.mLDLR vector in high fat fed Ldlr-/-Apobec1-/- mice.

Plasma lipoprotein profiles and leukocyte count in WT mice and LDLr−/− mice on normal and high-fat diet.

Yingmei Feng (122603)
Sarah Schouteden (102917)
Rachel Geenens (122605)
Vik Van Duppen (122606)
Paul Herijgers (122608)
Paul Holvoet (122610)
Paul P. Van Veldhoven (122613)
Catherine M. Verfaillie (67806)

November 2012

Cholesterol data are expressed as mg/dl and presented as means ± SEM. Peripheral white blood cell...

Total and non-HDL, VLDL, IDL, LDL, and HDL plasma cholesterol (mg/dl) at day 14 after saline injection or gene transfer with 5×1010 particles of Adnull (Controls), after gene transfer with 5×1010 particles of AdLDLr, and after gene transfer with 5×1010 particles of AdA-I in female C57BL/6 LDLr−/− mice fed a diet containing 0.2% cholesterol, 10% coconut oil.

Stephanie C. Gordts (129007)
Eline Van Craeyveld (129011)
Ilayaraja Muthuramu (129015)
Neha Singh (129019)
Frank Jacobs (129023)
Bart De Geest (129026)

October 2012

Data are expressed as means ± SEM (n = 10 for each condition). Lipoproteins were isolated by ultr...

Yazaki Y. Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E: accelerated clearance of lipoproteins containing apolipoprotein B. / Clin Invest

Hitoshi Shimano
Nobuhiro Yamada
Motoya Katsuki
Koji Yamamoto
Takanari Gotoda
Kenji Harada
Masako Shimada

September 2016

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma chol...

Evaluation of the minimum effective dose of AAV.TBG.mLDLR vector in Ldlr-/-Apobec1-/- Mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

Amounts of (A) Plasma cholesterol and (B) non-HDL cholesterol were evaluated in Ldlr-/-Apobec1...

Evaluation of AAV8 encoding mouse Vldlr or mouse Ldlr in Ldlr-/-Apobec1-/- Mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

(A) Plasma cholesterol levels in Ldlr-/-Apobec1-/- mice after treatment with AAV8.TBG.m...

AAV8.TBG.mLDLR mediated regression of atherosclerotic lesions in high-fat fed Ldlr-/-Apobec1-/-mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

(A) En face Sudan IV staining. Mouse aortas were pinned and stained with Sudan IV, which stains n...

Lipid levels of Ldlr-/- and Ldlr-/-Batf3-/- mice fed a high fat diet for 8 weeks.

Jesus Gil-Pulido (4329820)
Clement Cochain (4329817)
Malte A. Lippert (4329823)
Nicole Schneider (3076530)
Elke Butt (46105)
Núria Amézaga (479638)
Alma Zernecke (92960)

August 2017

Lipid levels of Ldlr-/- and Ldlr-/-Batf3...

Plasma HDL cholesterol, LDL/VLDL cholesterol, and ketone body levels in Ad-infected mice.

Yinfang Wang (444738)
Yahui Zhang (444739)
Hang Qian (444740)
Juan Lu (275293)
Zhifeng Zhang (444741)
Xinwen Min (290264)
Mingjian Lang (290277)
Handong Yang (290283)
Nanping Wang (408534)
Peng Zhang (2071)

August 2013

Mice were infected with the indicated adenovirus vector for 4 days. Fasting plasma HDL cholestero...

Plasma lipoprotein cholesterol and triglyceride profiles for apoE−/− and LDLr−/− mice.

Patricia L. Mitchell (111080)
Tobias K. Karakach (111084)
Deborah L. Currie (111088)
Roger S. McLeod (111094)

December 2012

After 11 weeks on a HFC diet supplemented with 0.5% (w/w) of the indicated fatty acid, serum was ...

Normal production rate of apolipoprotein B

John S. Millar
Cyrille Maugeais
Ilia V. Fuki
Daniel J. Rader
Triton Wr Apobec

January 2002

Abstract—The low density lipoprotein (LDL) receptor is well known for its role in mediating the remo...

Hyperlipidemia and Atherosclerotic Lesion Development in LDL Receptor Deficient Mice Fed Defined Semipurified Diets With and Without Cholate

Lichtman, Andrew Harry
Clinton, S. K.
Iiyama, K.
Connelly, P. W.
Libby, Peter
Cybulsky, M. I.

January 1999

Past studies of atherosclerosis in mice have used chow-based diets supplemented with cholesterol, li...

Upregulation of liver VLDL receptor and FAT/CD36 expressions in LDLR-/- apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid

Degrace, Pascal
Moindrot, Bastien
Mohamed, Ismaël
Gresti, Joseph
Du, Zhen-Yu
Chardigny, Jean-Michel
Sébédio, Jean-Louis
Clouet, Pierre

January 2006

This study explores the mechanisms responsible for the fatty liver setup in mice fed trans-10,cis-12...

Hypercholesterolemia in AAVmPcsk9-injected, Western diet-fed mice can be reversed by a diet switch and MTPi treatment.

Michael Peled (3836692)
Hitoo Nishi (634642)
Ada Weinstock (3836683)
Tessa J. Barrett (785028)
Felix Zhou (3836689)
Alexandra Quezada (3836686)
Edward A. Fisher (155431)

March 2017

A. Experimental design: C57BL/6J mice were i.p. injected once with AAVmPcsk9 and were plac...

Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).

Sanan, D.A.
Newland, D.L.
Tao, R.
Marcovina, S.
Wang, J.
Mooser, V.
Hammer, R.E.
Hobbs, H.H.

January 1998

We have generated mice with markedly elevated plasma levels of human low density lipoprotein (LDL) a...

Adeno-associated virus LPL(S447X) gene therapy in LDL receptor knockout mice

Rip, Jaap
Sierts, Jeroen A.
Vaessen, Stefan F. C.
Kastelein, John J. P.
Twisk, Jaap
Kuivenhoven, Jan Albert

January 2007

BACKGROUND: Overexpression of lipoprotein lipase (LPL) protects against atherosclerosis in genetical...

Plasma lipoprotein profiles and leukocyte count in WT mice and LDLr−/− mice on normal and high-fat diet.

Yingmei Feng (122603)
Sarah Schouteden (102917)
Rachel Geenens (122605)
Vik Van Duppen (122606)
Paul Herijgers (122608)
Paul Holvoet (122610)
Paul P. Van Veldhoven (122613)
Catherine M. Verfaillie (67806)

November 2012

Cholesterol data are expressed as mg/dl and presented as means ± SEM. Peripheral white blood cell...

Total and non-HDL, VLDL, IDL, LDL, and HDL plasma cholesterol (mg/dl) at day 14 after saline injection or gene transfer with 5×1010 particles of Adnull (Controls), after gene transfer with 5×1010 particles of AdLDLr, and after gene transfer with 5×1010 particles of AdA-I in female C57BL/6 LDLr−/− mice fed a diet containing 0.2% cholesterol, 10% coconut oil.

Stephanie C. Gordts (129007)
Eline Van Craeyveld (129011)
Ilayaraja Muthuramu (129015)
Neha Singh (129019)
Frank Jacobs (129023)
Bart De Geest (129026)

October 2012

Data are expressed as means ± SEM (n = 10 for each condition). Lipoproteins were isolated by ultr...

Yazaki Y. Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E: accelerated clearance of lipoproteins containing apolipoprotein B. / Clin Invest

Hitoshi Shimano
Nobuhiro Yamada
Motoya Katsuki
Koji Yamamoto
Takanari Gotoda
Kenji Harada
Masako Shimada

September 2016

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma chol...

Evaluation of the minimum effective dose of AAV.TBG.mLDLR vector in Ldlr-/-Apobec1-/- Mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

Amounts of (A) Plasma cholesterol and (B) non-HDL cholesterol were evaluated in Ldlr-/-Apobec1...

Evaluation of AAV8 encoding mouse Vldlr or mouse Ldlr in Ldlr-/-Apobec1-/- Mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

(A) Plasma cholesterol levels in Ldlr-/-Apobec1-/- mice after treatment with AAV8.TBG.m...

AAV8.TBG.mLDLR mediated regression of atherosclerotic lesions in high-fat fed Ldlr-/-Apobec1-/-mice.

Sadik H. Kassim (360646)
Hui Li (32376)
Luk H. Vandenberghe (262393)
Christian Hinderer (360649)
Peter Bell (277811)
Dawn Marchadier (360650)
Aisha Wilson (360651)
Debra Cromley (360652)
Valeska Redon (360653)
Hongwei Yu (3139)
James M. Wilson (262417)
Daniel J. Rader (113673)

February 2013

(A) En face Sudan IV staining. Mouse aortas were pinned and stained with Sudan IV, which stains n...

Lipid levels of Ldlr-/- and Ldlr-/-Batf3-/- mice fed a high fat diet for 8 weeks.

Jesus Gil-Pulido (4329820)
Clement Cochain (4329817)
Malte A. Lippert (4329823)
Nicole Schneider (3076530)
Elke Butt (46105)
Núria Amézaga (479638)
Alma Zernecke (92960)

August 2017

Lipid levels of Ldlr-/- and Ldlr-/-Batf3...

Plasma HDL cholesterol, LDL/VLDL cholesterol, and ketone body levels in Ad-infected mice.

Yinfang Wang (444738)
Yahui Zhang (444739)
Hang Qian (444740)
Juan Lu (275293)
Zhifeng Zhang (444741)
Xinwen Min (290264)
Mingjian Lang (290277)
Handong Yang (290283)
Nanping Wang (408534)
Peng Zhang (2071)

August 2013

Mice were infected with the indicated adenovirus vector for 4 days. Fasting plasma HDL cholestero...

Plasma lipoprotein cholesterol and triglyceride profiles for apoE−/− and LDLr−/− mice.

Patricia L. Mitchell (111080)
Tobias K. Karakach (111084)
Deborah L. Currie (111088)
Roger S. McLeod (111094)

December 2012

After 11 weeks on a HFC diet supplemented with 0.5% (w/w) of the indicated fatty acid, serum was ...

Normal production rate of apolipoprotein B

John S. Millar
Cyrille Maugeais
Ilia V. Fuki
Daniel J. Rader
Triton Wr Apobec

January 2002

Abstract—The low density lipoprotein (LDL) receptor is well known for its role in mediating the remo...

Hyperlipidemia and Atherosclerotic Lesion Development in LDL Receptor Deficient Mice Fed Defined Semipurified Diets With and Without Cholate

Lichtman, Andrew Harry
Clinton, S. K.
Iiyama, K.
Connelly, P. W.
Libby, Peter
Cybulsky, M. I.

January 1999

Past studies of atherosclerosis in mice have used chow-based diets supplemented with cholesterol, li...

Upregulation of liver VLDL receptor and FAT/CD36 expressions in LDLR-/- apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid

Degrace, Pascal
Moindrot, Bastien
Mohamed, Ismaël
Gresti, Joseph
Du, Zhen-Yu
Chardigny, Jean-Michel
Sébédio, Jean-Louis
Clouet, Pierre

January 2006

This study explores the mechanisms responsible for the fatty liver setup in mice fed trans-10,cis-12...

Hypercholesterolemia in AAVmPcsk9-injected, Western diet-fed mice can be reversed by a diet switch and MTPi treatment.

Michael Peled (3836692)
Hitoo Nishi (634642)
Ada Weinstock (3836683)
Tessa J. Barrett (785028)
Felix Zhou (3836689)
Alexandra Quezada (3836686)
Edward A. Fisher (155431)

March 2017

A. Experimental design: C57BL/6J mice were i.p. injected once with AAVmPcsk9 and were plac...

Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).

Sanan, D.A.
Newland, D.L.
Tao, R.
Marcovina, S.
Wang, J.
Mooser, V.
Hammer, R.E.
Hobbs, H.H.

January 1998

We have generated mice with markedly elevated plasma levels of human low density lipoprotein (LDL) a...

Adeno-associated virus LPL(S447X) gene therapy in LDL receptor knockout mice

Rip, Jaap
Sierts, Jeroen A.
Vaessen, Stefan F. C.
Kastelein, John J. P.
Twisk, Jaap
Kuivenhoven, Jan Albert

January 2007

BACKGROUND: Overexpression of lipoprotein lipase (LPL) protects against atherosclerosis in genetical...

Plasma lipoprotein profiles and leukocyte count in WT mice and LDLr−/− mice on normal and high-fat diet.

Yingmei Feng (122603)
Sarah Schouteden (102917)
Rachel Geenens (122605)
Vik Van Duppen (122606)
Paul Herijgers (122608)
Paul Holvoet (122610)
Paul P. Van Veldhoven (122613)
Catherine M. Verfaillie (67806)

November 2012

Cholesterol data are expressed as mg/dl and presented as means ± SEM. Peripheral white blood cell...

Total and non-HDL, VLDL, IDL, LDL, and HDL plasma cholesterol (mg/dl) at day 14 after saline injection or gene transfer with 5×1010 particles of Adnull (Controls), after gene transfer with 5×1010 particles of AdLDLr, and after gene transfer with 5×1010 particles of AdA-I in female C57BL/6 LDLr−/− mice fed a diet containing 0.2% cholesterol, 10% coconut oil.

Stephanie C. Gordts (129007)
Eline Van Craeyveld (129011)
Ilayaraja Muthuramu (129015)
Neha Singh (129019)
Frank Jacobs (129023)
Bart De Geest (129026)

October 2012

Data are expressed as means ± SEM (n = 10 for each condition). Lipoproteins were isolated by ultr...

Yazaki Y. Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E: accelerated clearance of lipoproteins containing apolipoprotein B. / Clin Invest

Hitoshi Shimano
Nobuhiro Yamada
Motoya Katsuki
Koji Yamamoto
Takanari Gotoda
Kenji Harada
Masako Shimada

September 2016

We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma chol...

Evaluation of AAV8.TBG.<i>mLDLR</i> vector in high fat fed <i>Ldlr-/-Apobec1-/-</i> mice.

Abstract

Extracted data

Evaluation of AAV8.TBG.<i>mLDLR</i> vector in high fat fed <i>Ldlr-/-Apobec1-/-</i> mice.

Abstract

Extracted data

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