Short-term recording of SBP and HR after an acute treatment with L-NAME (A–D) and phenylephrine (E–H).

<p>Recording of cardiovascular parameters was assessed in 9-mo male C57BL6 mice (<i>exp1</i>) during 1 h in n = 5 animals per group. Values are presented as mean values of SBP or HR ± SEM calculated for each 5 minutes sequence of recording. Arrows indicate the time of injection. Δ values of SBP and HR were calculated by subtracting the mean values of the 5 time-point after to the mean values of the 5 time-point before injection. Statistical analysis by Two-way ANOVA indicates a significant influence of post-weaning OB diet (P = 0.0127) as well as a significant influence of maternal LP diet (P = 0.0429) for ΔHR after phenylephrine treatment.