Chemical, geometric and kinetic/thermodynamic parameters used in the model.

[a]<p>average concentration found in human blood.</p>[b]<p>protein radius calculated as if each protein were spherical.</p>[c]<p>starting concentration in the simulation.</p>[d]<p>association rate constant; see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010949#s3" target="_blank">Materials and Methods</a> section for details.</p>[e]<p>dissociation rate constant: see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010949#s3" target="_blank">Materials and Methods</a> section for details.</p>[f]<p>equilibrium constant (K_A = <i>k^on</i>/<i>k^off</i>).</p>[g]<p>ideal number of binding sites on the nanoparticle surface for the protein <i>i</i>.</p>[h]<p>see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010949#s3" target="_blank">Materials and Methods</a> section for details.</p>[i]<p>average values for a healthy adult human <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010949#pone.0010949-Anderson1" target="_blank">[18]</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010949#pone.0010949-Hortin1" target="_blank">[20]</a>.