Additional file 2: Figure S2. of Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice

Blue Brilliant FCF treatment reduced CCI-induced pro-inflammatory cytokines. Administration of Blue Brilliant FCF via intraperitoneal injection (60 mg/kg) was performed 1 h post-CCI. Gene expression levels determined by qPCR for IL-1b, TNF-α, and IL-6 were measured 1 day post-injury. Values are expressed as mean fold change (± SEM) relative to sham (n = 8). GAPDH was used as an endogenous control. Statistical significance was evaluated using one-way ANOVA followed by Tukey’s HSD. (DOCX 85 kb