High expression of CXCL12 in the CNS of mice with chronic clinical EAE. (a, b) Immunofluorescent images of spinal cord tissue sections (L1–L6) from mice with ongoing EAE (day 50 after immunization; clinical score =3) and from naive mice (a) immunostained for CXCL12 (red) or (b) co-stained for CXCL12 (green) and GFAP (red). (c) Immunofluorescent image of the cortex of the mice in panel a immunostained for CXCL12 (red). In a and c, nuclei were counterstained with DAPI (blue). Scale bars: a and c, 100 μm; b, 20 μm. (TIF 8873 kb
Figure S1. Qualitative immunohistochemical staining for CSF1R receptor (red) in mouse brain cortex s...
Figure S1. The numbers of CNS-infiltrating myeloid cells are comparable at the onset of cEAE and aEA...
TNF blockade reduces astrocyte and myeloid cell reactivity during progressive EAE in GFAPγR1Δ mice. ...
The CXCL12 expression, CXCL12+ NPCs and CXCL12+ OPCs in the DG and CC of mice that did not recover f...
In vitro differentiation of aNSCs isolated from the subventricular zone of adult mice. Neurospheres ...
CXCR3-/- mice have increased mononuclear cells infiltrating in the spinal cord as compared with WT m...
BBB permeability of control and Cstb −/− mice. (A) Levels of sodium fluorescein (NaF) in the brain o...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S2. The immunofluorescent staining of CX3CL1 on microglia or astrocytes. (A) Double immunoflu...
MCP1+ cells and CCR2+ cells are present in the motor cortex and they are in close proximity to CSMN ...
PET and MRI images of EAE mice at 14 days p.i. In vivo PET and MRI representative images of three of...
Specific eGFP expression of astroglial cells in Aldh1l1-EGFP mice. Confocal micrographs showing astr...
Detection of cerebellar demyelination, axonal damage, and remyelination in MP4-immunized mice. (a) L...
Quantification of Npas4 and Bdnf RNA in mouse spinal cords over the course of EAE. Tissues from 5 to...
Comparison between Iba-1-labeled microglial cells in the motor cortex of WT mice and intense symptom...
Figure S1. Qualitative immunohistochemical staining for CSF1R receptor (red) in mouse brain cortex s...
Figure S1. The numbers of CNS-infiltrating myeloid cells are comparable at the onset of cEAE and aEA...
TNF blockade reduces astrocyte and myeloid cell reactivity during progressive EAE in GFAPγR1Δ mice. ...
The CXCL12 expression, CXCL12+ NPCs and CXCL12+ OPCs in the DG and CC of mice that did not recover f...
In vitro differentiation of aNSCs isolated from the subventricular zone of adult mice. Neurospheres ...
CXCR3-/- mice have increased mononuclear cells infiltrating in the spinal cord as compared with WT m...
BBB permeability of control and Cstb −/− mice. (A) Levels of sodium fluorescein (NaF) in the brain o...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S2. The immunofluorescent staining of CX3CL1 on microglia or astrocytes. (A) Double immunoflu...
MCP1+ cells and CCR2+ cells are present in the motor cortex and they are in close proximity to CSMN ...
PET and MRI images of EAE mice at 14 days p.i. In vivo PET and MRI representative images of three of...
Specific eGFP expression of astroglial cells in Aldh1l1-EGFP mice. Confocal micrographs showing astr...
Detection of cerebellar demyelination, axonal damage, and remyelination in MP4-immunized mice. (a) L...
Quantification of Npas4 and Bdnf RNA in mouse spinal cords over the course of EAE. Tissues from 5 to...
Comparison between Iba-1-labeled microglial cells in the motor cortex of WT mice and intense symptom...
Figure S1. Qualitative immunohistochemical staining for CSF1R receptor (red) in mouse brain cortex s...
Figure S1. The numbers of CNS-infiltrating myeloid cells are comparable at the onset of cEAE and aEA...
TNF blockade reduces astrocyte and myeloid cell reactivity during progressive EAE in GFAPγR1Δ mice. ...