Additional file 9: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Additional file 17: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S8. Aberrant methylation in the upstream regions of NSD1. Visualizing the methylation levels ...

Additional file 20: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S11. Aberrant methylation in the upstream regions of SUV39H1. Visualizing the methylation lev...

Additional file 16: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S7. Aberrant methylation in the upstream regions of SOX3. Visualizing the methylation levels ...

Additional file 2: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Scatter plots of genome-wide DNA methylation discordance within twin groups. (PPTX 331Â kb

Additional file 11: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

CpG sites (probes) within each twin pair group with an absolute methylation difference >â0.5 and t...

Additional file 1: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Primer sequences used in site-specific validation using MassArray EpiTYPER. (XLSX 8Â kb

Additional file 6: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Gene ontology (GO) analysis for top-ranked 1000 DMPs ranked by p value. (XLSX 20Â kb

Additional file 4: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

MDS plots for preprocessed data. Samples are coloured based on chip location ranging from 1 to 3. Th...

Additional file 8: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Cross-platform validation of the two top DMRs, LTA and LIME1, between HM450 and EpiTYPER platforms. ...

Additional file 3: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Heat map of the associations between the six largest principal components and specified covariates. ...

Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Mohandas, N
Bass-Stringer, S
Maksimovic, J
Crompton, K
Loke, YJ
Walstab, J
Reid, SM
Amor, DJ
Reddihough, D
Craig, JM

February 2018

Background: Cerebral palsy (CP) is a clinical description for a group of motor disorders that are he...

Additional file 19: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S10. Aberrant methylation in the upstream regions of MECP2. Visualizing the methylation level...

Additional file 14: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S5. Aberrant methylation in the upstream regions of CITED1. Visualizing the methylation level...

Additional file 9: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S4. Comparison of systemic changes of methylome between two samples. (A) Cumulative depth dis...

Additional file 18: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S9. Aberrant methylation in the upstream regions of MTA2. Visualizing the methylation levels ...

Additional file 17: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S8. Aberrant methylation in the upstream regions of NSD1. Visualizing the methylation levels ...

Additional file 20: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S11. Aberrant methylation in the upstream regions of SUV39H1. Visualizing the methylation lev...

Additional file 16: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S7. Aberrant methylation in the upstream regions of SOX3. Visualizing the methylation levels ...

Additional file 2: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Scatter plots of genome-wide DNA methylation discordance within twin groups. (PPTX 331Â kb

Additional file 11: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

CpG sites (probes) within each twin pair group with an absolute methylation difference >â0.5 and t...

Additional file 1: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Primer sequences used in site-specific validation using MassArray EpiTYPER. (XLSX 8Â kb

Additional file 6: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Gene ontology (GO) analysis for top-ranked 1000 DMPs ranked by p value. (XLSX 20Â kb

Additional file 4: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

MDS plots for preprocessed data. Samples are coloured based on chip location ranging from 1 to 3. Th...

Additional file 8: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Cross-platform validation of the two top DMRs, LTA and LIME1, between HM450 and EpiTYPER platforms. ...

Additional file 3: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Namitha Mohandas (278371)
Sebastian Bass-Stringer (3861313)
Jovana Maksimovic (4877497)
Kylie Crompton (4877488)
Yuk Loke (3448697)
Janet Walstab (4877500)
Susan Reid (3447206)
David Amor (4877491)
Dinah Reddihough (4877494)
Jeffrey Craig (3448721)

February 2018

Heat map of the associations between the six largest principal components and specified covariates. ...

Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Mohandas, N
Bass-Stringer, S
Maksimovic, J
Crompton, K
Loke, YJ
Walstab, J
Reid, SM
Amor, DJ
Reddihough, D
Craig, JM

February 2018

Background: Cerebral palsy (CP) is a clinical description for a group of motor disorders that are he...

Additional file 19: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S10. Aberrant methylation in the upstream regions of MECP2. Visualizing the methylation level...

Additional file 14: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S5. Aberrant methylation in the upstream regions of CITED1. Visualizing the methylation level...

Additional file 9: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S4. Comparison of systemic changes of methylome between two samples. (A) Cumulative depth dis...

Additional file 18: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S9. Aberrant methylation in the upstream regions of MTA2. Visualizing the methylation levels ...

Additional file 17: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S8. Aberrant methylation in the upstream regions of NSD1. Visualizing the methylation levels ...

Additional file 20: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S11. Aberrant methylation in the upstream regions of SUV39H1. Visualizing the methylation lev...

Additional file 16: of Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

Guoliang Lyu (410554)
Chao Zhang (4202110)
Te Ling (410551)
Rui Liu (54031)
Le Zong (410553)
Yiting Guan (5337593)
Xiaoke Huang (445052)
Lei Sun (45752)
Lijun Zhang (483325)
Cheng Li (6339)
Yu Nie (217939)
Wei Tao (410556)

June 2018

Figure S7. Aberrant methylation in the upstream regions of SOX3. Visualizing the methylation levels ...

Additional file 9: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Abstract

Extracted data

Additional file 9: of Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation

Abstract

Extracted data

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