Additional file 3: of Nanog induced intermediate state in regulating stem cell differentiation and reprogramming

Figure S2. The simplified two-dimensional Oct4-Nanog model on the phase plate and the distribution of Oct4. (A)The nullclines and the vector field of the simplified two-dimensional Oct4-Nanog model on the phase plate. A typical trajectory is illustrated to indicate the excitable mechanism of the model. (d[Oct4]/dt = 0: Red line; d[Nanog]/dt = 0: Blue line.) (B) Distributions of Sox2 level within simulated cell population (N = 10,000). (PDF 102 kb