<p>(*)In agreement with the fast degradation of the engineered proteins in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000704#pcbi.1000704-Elowitz1" target="_blank">[38]</a>.</p
<p>We consider a 2-stage model of gene expression with the input, , equal to the current rate of tra...
a<p>Values for these rate and equilibrium constants were calculated based on the information in the ...
<p>The ability of the simulated trajectories to reproduce the experimentally observed data of distri...
<p>They are the same as those used by <a href="http://www.plosone.org/article/info:doi/10.1371/journ...
<p>The simulations shown are identical to that displayed in <a href="http://www.plosone.org/article/...
<p><b>A</b>. Degradation rate versus free substrate concentration [S] for the control parameters sho...
<p>Using experimental data and first-order decay curves, degradation coefficients of (A) Vif, (B) A3...
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>The data were calculated using the stochastic simulation method. The R protein degradation rate ...
<p>The R protein degradation rate with the dynamics calculated with the stochastic algorithm. The r...
<p>Indexes of variables are A (as in k<sub>A</sub>, V<sub>A</sub>) for control (+DMSO) and B (as in ...
<p>The rate constant is set equal to <i>k</i><sub>3</sub> throughout the work, whereas , and may d...
<p>The main plot shows peak integrals normalized to molar fractions of the initial SPI2-SRHWAP-His<s...
<p>(<b>A</b>) A cleavable tag is fused N-terminally to the target protein. On cleavage, an N-degron ...
<p>Different conditions correspond to different treatments (see right panel of <a href="http://www.p...
<p>We consider a 2-stage model of gene expression with the input, , equal to the current rate of tra...
a<p>Values for these rate and equilibrium constants were calculated based on the information in the ...
<p>The ability of the simulated trajectories to reproduce the experimentally observed data of distri...
<p>They are the same as those used by <a href="http://www.plosone.org/article/info:doi/10.1371/journ...
<p>The simulations shown are identical to that displayed in <a href="http://www.plosone.org/article/...
<p><b>A</b>. Degradation rate versus free substrate concentration [S] for the control parameters sho...
<p>Using experimental data and first-order decay curves, degradation coefficients of (A) Vif, (B) A3...
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>The data were calculated using the stochastic simulation method. The R protein degradation rate ...
<p>The R protein degradation rate with the dynamics calculated with the stochastic algorithm. The r...
<p>Indexes of variables are A (as in k<sub>A</sub>, V<sub>A</sub>) for control (+DMSO) and B (as in ...
<p>The rate constant is set equal to <i>k</i><sub>3</sub> throughout the work, whereas , and may d...
<p>The main plot shows peak integrals normalized to molar fractions of the initial SPI2-SRHWAP-His<s...
<p>(<b>A</b>) A cleavable tag is fused N-terminally to the target protein. On cleavage, an N-degron ...
<p>Different conditions correspond to different treatments (see right panel of <a href="http://www.p...
<p>We consider a 2-stage model of gene expression with the input, , equal to the current rate of tra...
a<p>Values for these rate and equilibrium constants were calculated based on the information in the ...
<p>The ability of the simulated trajectories to reproduce the experimentally observed data of distri...