Simulation condition-independent rate and equilibrium constants.

a<p>Values for these rate and equilibrium constants were calculated based on the information in the literature. Details of the calculation are described in the <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003461#s3" target="_blank">Materials and Methods</a> section.</p>b<p>Values for these rate and equilibrium constants were assumed in this study.</p>c<p>Values for these rate and equilibrium constants were obtained from the literature <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003461#pcbi.1003461-Yang1" target="_blank">[12]</a>.