Phenotypic ETV Resistance of HBV Clones.

a<p>EC₅₀ and IC₅₀ values represent the mean ± standard deviation (SD) from at least 3 independent experiments.</p>b<p>Wildtype values from a single isolate tested in parallel <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009195#pone.0009195-Tenney1" target="_blank">[5]</a>, the average ETV EC₅₀ for a panel of 76 wildtype isolates = 3.4±2.0 nM.</p>c<p>LVDr values from a single isolate tested in parallel <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009195#pone.0009195-Tenney1" target="_blank">[5]</a>, the average ETV EC₅₀ for a panel of 15 LVDr isolates = 31.1±17.5 nM.</p>d<p>Values averaged from 2 independent isolates.</p>e<p>Values obtained from a single patient isolate <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009195#pone.0009195-Tenney1" target="_blank">[5]</a>.