<p>From one to six random mutations were simulated in each model 500 times. Mutants were considered viable if they correctly completed their cell cycles when analyzed with a synchronous update rule. However, mutations tended to reduce timing robustness even in the viable mutants, indicating that timing robustness is maintained by selection.</p
The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutati...
Natural selection is commonly assumed to act on extensive standing genetic variation. Yet, accumulat...
Mutations are the heritable changes in DNA which make evolution possible. Natural selection acts on ...
<p>The model was run for 500 timesteps to allow the cell populations to equilibrate before a mutant ...
Gene expression is a stochastic biological processes that controls the different phenotypes of an or...
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the gen...
Whether evolution can be predicted is a key question in evolutionary biology. Here we set out to bet...
<p><b>Copyright information:</b></p><p>Taken from "Evolution favors protein mutational robustness in...
For evolving populations of replicators, there is much evidence that the effect of mutations on fitn...
<p>Mutation accumulation was modeled as a sequential process in which each genotype can acquire a si...
<p>We tested how extrinsic parameter variations in the regulation of the transcriptionally controlle...
<p><b>Copyright information:</b></p><p>Taken from "Evolution favors protein mutational robustness in...
<p>Each square represents a set of simulations with identical gene expression noise level and mutati...
We review recent advances in the understanding of the mutation-selection balance of asexual replicat...
Understanding the effect of population size on the key parameters of evolution is particularly impor...
The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutati...
Natural selection is commonly assumed to act on extensive standing genetic variation. Yet, accumulat...
Mutations are the heritable changes in DNA which make evolution possible. Natural selection acts on ...
<p>The model was run for 500 timesteps to allow the cell populations to equilibrate before a mutant ...
Gene expression is a stochastic biological processes that controls the different phenotypes of an or...
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the gen...
Whether evolution can be predicted is a key question in evolutionary biology. Here we set out to bet...
<p><b>Copyright information:</b></p><p>Taken from "Evolution favors protein mutational robustness in...
For evolving populations of replicators, there is much evidence that the effect of mutations on fitn...
<p>Mutation accumulation was modeled as a sequential process in which each genotype can acquire a si...
<p>We tested how extrinsic parameter variations in the regulation of the transcriptionally controlle...
<p><b>Copyright information:</b></p><p>Taken from "Evolution favors protein mutational robustness in...
<p>Each square represents a set of simulations with identical gene expression noise level and mutati...
We review recent advances in the understanding of the mutation-selection balance of asexual replicat...
Understanding the effect of population size on the key parameters of evolution is particularly impor...
The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutati...
Natural selection is commonly assumed to act on extensive standing genetic variation. Yet, accumulat...
Mutations are the heritable changes in DNA which make evolution possible. Natural selection acts on ...