Processes, functions and pathways altered by RWE challenge.

<p>Genes altered by RWE challenge were analyzed using the Ingenuity Pathway Analysis (IPA) knowledge database. Cellular Processes (A) and Immune Response (B) were the top two processes affected. Bar graphs show functions/pathways within each process significantly altered by RWE challenge (P<0.05). The Y-axis denotes the significance of altering that particular function; a higher bar means greater significance. The yellow line is the cut-off for the significance level and coincides with a P value of 0.05. The number above each bar denotes the number of genes in that particular function that were significantlyaltered by RWE challenge (P<0.01).