Administration of <i>M. leprae</i> rHsp65 increased EAU scores.

<p>[<i>A</i>]: B10.RIII mice were immunized with 161–180 IRBP peptide followed by injection with rHsp65 [i.p.]. Eyes were collected for histopathology 21 days later. EAU scores were assigned on a 0 to 4 scale. [<i>B</i>]: Histopathological findings: a normal retinal architecture corresponding to non immunized <i>naïve</i> mice [<i>normal</i>]; IRBP immunized mice [average score 3; <i>control</i>]; mice immunized with IRBP followed by rHsp65 inoculation [average score 4; <i>rHsp65</i>]. Representative photographs [hematoxilin-eosin staining] of three independent experiments with n = 6–8 mice/group. Magnification: 200x.