<p>BALB/c (A), NUDE (B), SCID (C), and SCID BEIGE (D) mice. <i>B. duttonii</i> established infection in all four mouse strains. Spirochetemia was significantly (p = 0.02) higher in B-cell-deficient mice (C, D). No differences were observed between wild-type and T-cell-deficient mice (A vs. B) or between SCID mice and NK-cell-deficient SCID BEIGE mice (C vs. D). Data are presented as medians with 25<sup>th</sup> and 75<sup>th</sup> percentiles. Notice that the scales of the y-axes in this figure differ from those in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000522#pntd-0000522-g002" target="_blank">Figures 2</a> and <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000522#pntd-0000522-g004"...
<p><b>5. Illness with delayed onset in C3<sup>−/−</sup> mice in low-dose </b><b><i>C. psittaci</i></...
<p>(A) Comparison between wild-type (<i>BBEE</i>) and C/EBPβ<sup>−/−</sup>C/EBPε<sup>−/−</sup> (<i>b...
Groups of 4–6 immunocompetent C3H/HeN mice were needle inoculated intradermally with 104 B. burgdorf...
<p><i>B. recurrentis</i> established a relatively low-grade (compared to <i>B. duttonii</i>, see <a ...
<p>Each data point represents the number of spirochetes per ml of blood for an individual mouse duri...
<p>Five SCID mice and 1 wild-type mouse with the same genetic background (C3H/HeSnJ) were injected i...
<p>Each data point represents the number of spirochetes per ml of blood for an individual mouse duri...
<p>Immunoblot analysis of sera collected three weeks post inoculation from groups of five C3H/HeN mi...
<p>Whole-cell lysates of wild-type spirochetes were separated by PAGE, transferred to nitrocellulose...
<p>RML mice were injected ip with 500 spirochetes of the wild-type (WT), Vmp<sup>−</sup> mutant (Vmp...
<p>Kinetics of spirochetemia with wild-type <i>B. hermsii</i> (A), <i>B. hermsii fliH</i> mutant (B)...
<p><b>8. Bacterial load in spleen of infected C3<sup>−/−</sup> and WT mice.</b> Mice were infected w...
<p>In the epididymis (A–C; 21 days post inoculation (DPI)), spirochetes are present in large numbers...
<p>Mice orally infected with spores from the <i>csB</i> mutant show high levels of spores shed from ...
<p>A. Mice were infected with either 10<sup>5</sup> wild type <i>L. major</i> (squares) or 10<sup>5<...
<p><b>5. Illness with delayed onset in C3<sup>−/−</sup> mice in low-dose </b><b><i>C. psittaci</i></...
<p>(A) Comparison between wild-type (<i>BBEE</i>) and C/EBPβ<sup>−/−</sup>C/EBPε<sup>−/−</sup> (<i>b...
Groups of 4–6 immunocompetent C3H/HeN mice were needle inoculated intradermally with 104 B. burgdorf...
<p><i>B. recurrentis</i> established a relatively low-grade (compared to <i>B. duttonii</i>, see <a ...
<p>Each data point represents the number of spirochetes per ml of blood for an individual mouse duri...
<p>Five SCID mice and 1 wild-type mouse with the same genetic background (C3H/HeSnJ) were injected i...
<p>Each data point represents the number of spirochetes per ml of blood for an individual mouse duri...
<p>Immunoblot analysis of sera collected three weeks post inoculation from groups of five C3H/HeN mi...
<p>Whole-cell lysates of wild-type spirochetes were separated by PAGE, transferred to nitrocellulose...
<p>RML mice were injected ip with 500 spirochetes of the wild-type (WT), Vmp<sup>−</sup> mutant (Vmp...
<p>Kinetics of spirochetemia with wild-type <i>B. hermsii</i> (A), <i>B. hermsii fliH</i> mutant (B)...
<p><b>8. Bacterial load in spleen of infected C3<sup>−/−</sup> and WT mice.</b> Mice were infected w...
<p>In the epididymis (A–C; 21 days post inoculation (DPI)), spirochetes are present in large numbers...
<p>Mice orally infected with spores from the <i>csB</i> mutant show high levels of spores shed from ...
<p>A. Mice were infected with either 10<sup>5</sup> wild type <i>L. major</i> (squares) or 10<sup>5<...
<p><b>5. Illness with delayed onset in C3<sup>−/−</sup> mice in low-dose </b><b><i>C. psittaci</i></...
<p>(A) Comparison between wild-type (<i>BBEE</i>) and C/EBPβ<sup>−/−</sup>C/EBPε<sup>−/−</sup> (<i>b...
Groups of 4–6 immunocompetent C3H/HeN mice were needle inoculated intradermally with 104 B. burgdorf...