<p>Genotypic fidelity is shown as mean pairwise distances among 19 paired comparisons of LCL and PBMC genotypes, for increasingly stringent SNP filtering by population call rate. A) Genotypic fidelity between LCL and PBMC source DNA from the same individual, estimated using the Affymetrix GeneChip Human Mapping 500 k Array set. B) SNP numbers remaining after filtering, shown for the combined 500 k array. C) Genotypic fidelity between LCL and PBMC source DNA from the same individual shown for the Nsp 250 k array. D) Genotypic fidelity between LCL and PBMC for the Sty 250 k array.</p
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
<p>Box plots indicate the posterior predictive distributions for each locus (1,000 replicates; horiz...
<p>Call rate refers to the percentage of called genotypes while the accuracy is computed as the numb...
<p>Relationship between genotypic fidelity of LCL and PBMC pairs (mismatch rate, estimated using pai...
a<p>LCL vs replicate PBMC.</p>b<p>PBMC vs replicate LCL.</p>c<p>PBMC vs replicate LCL.</p
Genotyping errors that are undetected in genome-wide association studies using single nucleotide pol...
High density single nucleotide polymorphism (SNP) genotyping panels provide an alternative to micros...
AbstractA simple method of inferring the genotyping error rate of SNP arrays and similar high-throug...
<div><p>(Red lines: inter-SNP distance = 12kb; green lines: inter-SNP distance = 120kb; blue lines: ...
<div><p>(A) The graph shows average values of |D′| and their confidence limits (± standard deviation...
The coefficient of variation of estimates of three genetic distances (standard genetic distance of N...
*<p><i>P</i>-values for Mann-Whitney U test (one sided, unequal sample sizes) comparing pairwise dis...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
The horizontal dashed line indicates the average linkage between markers on different chromosomes. L...
<p>Different nucleotide diversity was estimated using SNPs within the whole gene, π, nonsynonymous S...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
<p>Box plots indicate the posterior predictive distributions for each locus (1,000 replicates; horiz...
<p>Call rate refers to the percentage of called genotypes while the accuracy is computed as the numb...
<p>Relationship between genotypic fidelity of LCL and PBMC pairs (mismatch rate, estimated using pai...
a<p>LCL vs replicate PBMC.</p>b<p>PBMC vs replicate LCL.</p>c<p>PBMC vs replicate LCL.</p
Genotyping errors that are undetected in genome-wide association studies using single nucleotide pol...
High density single nucleotide polymorphism (SNP) genotyping panels provide an alternative to micros...
AbstractA simple method of inferring the genotyping error rate of SNP arrays and similar high-throug...
<div><p>(Red lines: inter-SNP distance = 12kb; green lines: inter-SNP distance = 120kb; blue lines: ...
<div><p>(A) The graph shows average values of |D′| and their confidence limits (± standard deviation...
The coefficient of variation of estimates of three genetic distances (standard genetic distance of N...
*<p><i>P</i>-values for Mann-Whitney U test (one sided, unequal sample sizes) comparing pairwise dis...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
The horizontal dashed line indicates the average linkage between markers on different chromosomes. L...
<p>Different nucleotide diversity was estimated using SNPs within the whole gene, π, nonsynonymous S...
Large samples and systematic screens of thousands of DNA markers are needed to detect quantitative t...
<p>Box plots indicate the posterior predictive distributions for each locus (1,000 replicates; horiz...
<p>Call rate refers to the percentage of called genotypes while the accuracy is computed as the numb...