Absence of galectin-3 leads to increased <i>P. brasiliensis</i> burden.

<p>Colony-forming units (CFU) recovered from lungs and liver (A) of gal3^+/+ (black bars) and gal3^−/− (open bars) mice 30 days after intraperitoneal (A) and intratracheal (B) infection with yeast cells. Relative quantification of <i>P. brasiliensis</i> in the lungs of infected mice 30 days after i.p. infection was carried out through real-time PCR (C). The bars represent the mean±SD of CFU obtained from duplicate samples in groups of five animals. * P<0.05, compared with infected gal3^+/+ mice.