<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by backbone atoms of residues of <sup>282</sup>LDLSNV<sup>287</sup> and (B,D) the corresponding average structures. (E) Aligned structures of the preserved cluster in ΔK280 ensembles, aligned by backbone atoms of residues <sup>282</sup>LDLSNV<sup>287</sup>. (F) The average conformation of the preserved cluster in ΔK280 ensembles. The location of S285 is shown in red in the average structures.</p
<p>Clustering was calculated from the inter-frame Cα RMSD of the 310 K replicas. The ranking of the ...
a<p>Distance constraints used for structure calculations, which excluded fixed intra-residue distanc...
<p>(A) The backbone trace of the structural ensembles of the 20 best-fit NMR structures of no Zn<sup...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A) Aligned structures for WT tau and (B) average backbone conformation for this cluster; (C) ali...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the holo structure (P...
<p>First, a six-residue local region is selected for analysis. Clusters of structures with similar c...
<p>(<b>a</b>) Cluster analysis of the MD conformations picked every 10 ps over the 96 ns of producti...
<p>Pairs of sites were superimposed on their 7 Cα atoms and the Cβ of the central S/T. Their pairwis...
<p>Each conformation was aligned to the IL-33 bound ST2 structure (grey color). The D1, D2, D3 domai...
<p>A) Plot of number of residue correspondences vs. RMSD in each structure (d1gt8a4 is in green, d1m...
Shown here are representative conformers of the α-synuclein ensemble shown in Fig 4. Structures A, B...
The statistical significance of the observed distribution can be estimated by comparing the respecti...
The \alpha / \beta barrel fold is adopted by most enzymes performing a variety of catalytic reaction...
<p>(A) A cartoon depiction of cluster of adjacent residues is shown (red circle). (B) Structural ali...
<p>Clustering was calculated from the inter-frame Cα RMSD of the 310 K replicas. The ranking of the ...
a<p>Distance constraints used for structure calculations, which excluded fixed intra-residue distanc...
<p>(A) The backbone trace of the structural ensembles of the 20 best-fit NMR structures of no Zn<sup...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A) Aligned structures for WT tau and (B) average backbone conformation for this cluster; (C) ali...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the holo structure (P...
<p>First, a six-residue local region is selected for analysis. Clusters of structures with similar c...
<p>(<b>a</b>) Cluster analysis of the MD conformations picked every 10 ps over the 96 ns of producti...
<p>Pairs of sites were superimposed on their 7 Cα atoms and the Cβ of the central S/T. Their pairwis...
<p>Each conformation was aligned to the IL-33 bound ST2 structure (grey color). The D1, D2, D3 domai...
<p>A) Plot of number of residue correspondences vs. RMSD in each structure (d1gt8a4 is in green, d1m...
Shown here are representative conformers of the α-synuclein ensemble shown in Fig 4. Structures A, B...
The statistical significance of the observed distribution can be estimated by comparing the respecti...
The \alpha / \beta barrel fold is adopted by most enzymes performing a variety of catalytic reaction...
<p>(A) A cartoon depiction of cluster of adjacent residues is shown (red circle). (B) Structural ali...
<p>Clustering was calculated from the inter-frame Cα RMSD of the 310 K replicas. The ranking of the ...
a<p>Distance constraints used for structure calculations, which excluded fixed intra-residue distanc...
<p>(A) The backbone trace of the structural ensembles of the 20 best-fit NMR structures of no Zn<sup...