<p>(A) Aligned structures for WT tau and (B) average backbone conformation for this cluster; (C) aligned structures for the ΔK280 mutant and (D) corresponding average structure. The backbone of PHF6* is shown in yellow for the average structures.</p
International audiencePhosphorylation of the microtubule-associated protein Tau influences the assem...
AbstractThe major constituent of Alzheimer’s disease paired helical filaments (PHF) core is intrinsi...
SummaryPhosphorylation of the microtubule-associated protein Tau influences the assembly and stabili...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the holo structure (P...
<p>First, a six-residue local region is selected for analysis. Clusters of structures with similar c...
<p>The secondary structure was generated using the STRIDE program implemented in VMD. Color scheme f...
<p>(<b>a</b>) Cluster analysis of the MD conformations picked every 10 ps over the 96 ns of producti...
The paradigmatic disordered protein tau plays an important role in neuronal function and neurodegene...
<p>Each conformation was aligned to the IL-33 bound ST2 structure (grey color). The D1, D2, D3 domai...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the native structure ...
<p>These clusters are identified based on the conformations sampled at 305 K during the last 60 ns o...
Protein backbone is represented as ribbons of the best 20 conformers during structure calculation.</...
Phosphorylation of the microtubule-associated protein Tau influences the assembly and stabilization ...
International audiencePhosphorylation of the microtubule-associated protein Tau influences the assem...
AbstractThe major constituent of Alzheimer’s disease paired helical filaments (PHF) core is intrinsi...
SummaryPhosphorylation of the microtubule-associated protein Tau influences the assembly and stabili...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A,C) Aligned structures corresponding to a preserved cluster in the WT ensembles aligned by back...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the holo structure (P...
<p>First, a six-residue local region is selected for analysis. Clusters of structures with similar c...
<p>The secondary structure was generated using the STRIDE program implemented in VMD. Color scheme f...
<p>(<b>a</b>) Cluster analysis of the MD conformations picked every 10 ps over the 96 ns of producti...
The paradigmatic disordered protein tau plays an important role in neuronal function and neurodegene...
<p>Each conformation was aligned to the IL-33 bound ST2 structure (grey color). The D1, D2, D3 domai...
<p>(A) The alignment of three randomly sampled conformations from Cluster 1 to the native structure ...
<p>These clusters are identified based on the conformations sampled at 305 K during the last 60 ns o...
Protein backbone is represented as ribbons of the best 20 conformers during structure calculation.</...
Phosphorylation of the microtubule-associated protein Tau influences the assembly and stabilization ...
International audiencePhosphorylation of the microtubule-associated protein Tau influences the assem...
AbstractThe major constituent of Alzheimer’s disease paired helical filaments (PHF) core is intrinsi...
SummaryPhosphorylation of the microtubule-associated protein Tau influences the assembly and stabili...
DOI
Add to ORKG