Distribution of the percentage of intrinsic disorder of chaperone-binding and non-chaperone-binding proteins in the three taxonomic groups.

<p>All the proteins detected in any kind of pairwise interactions in the IntAct database were taken into consideration. The percentage intrinsic disorder for each protein was calculated from disorder predicted by IUPred. The occurrence in each disorder range (with increments of 5% disorder) is given in % values, too, so that the area under each disorder curve amounts to 100. The median disorder values for the two sets of proteins are indicated in parentheses. (A) Bacteria (mostly <i>E. coli</i>). (B) Unicellular eukaryotes (mostly yeast). (C) Metazoa proteins.