<i>rbt1</i> and <i>rbt4</i> Mutants Colonize the Murine Intestinal Tract at WT Levels

<div><p>Cells of WT strains DAY185 or F2U, <i>rbt1</i> deletion mutant strain BCa 7–4, <i>rbt4</i> null mutant strain BCa 11–3, <i>ece1</i> null mutant CAW19–1, CKY362 (<i>ECE1</i> reconstituted), and CKY376 (<i>yhb1 yhb5</i> double null mutant) were orally inoculated by gavage. At various days post-inoculation, fresh fecal pellets were recovered from inoculated mice and the amount of C. albicans per gm was measured. Composite results of two experiments are shown. Different numbers of mice are shown on different days because some mice were sacrificed earlier and some mice were sampled on different days.</p><p>(A) Red circles, DAY185 or F2U (WT) (six mice); green triangles, <i>rbt1</i> deletion mutant strain BCa 7–4 (six mice); blue diamonds, <i>rbt4</i> deletion mutant strain Bca 11–3 (six mice); bars, geometric means.</p><p>(B) Red circles, DAY185 (WT) (six mice); green triangles, <i>yhb1 yhb5</i> double null mutant strain CKY376 (six mice); bars, geometric means.</p><p>(C) Red circles, DAY185 or F2U (WT) (six mice); green triangles, <i>ece1</i> deletion mutant strain CAW19–1 (six mice); black diamonds, <i>ECE1</i> reconstituted mutant strain CKY362 (four mice); bars, geometric means. Open symbols, no colonies detected. Day ≥ 14 indicates samples taken on day 14 or day 15.</p>