Average Fixation Time of Mutant SC

<p>The average fixation time of mutant SC depends on the relative fitness (A) (red, <i>r =</i> 1.02; blue, <i>r =</i> 1.05), population size (B), and probability of self-renewal (C) (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030053#pcbi-0030053-e009" target="_blank">Equation 9</a>). The fixation time for a neutral mutant is always the longest. Although mutants with reduced fitness can reach fixation quickly, this is an improbable event. In all figures, <i>n</i> = 10 (red), <i>n</i> = 50 (green), <i>n</i> = 100 (blue), and <i>n</i> = 400 (black).