Loss of Postsynaptic Target Cells but Not Local Striatal Interneurons in <i>DAT-Ret^lx/lx</i> Mice

<p>Immunohistochemical stainings of dorsal striatum of 2-y-old control (A, D, and G) and <i>DAT-Ret^lx/lx</i> mutants (B, E, and H) for NeuN (A and B), DARPP-32 (D and E), or parvalbumin (G and H). Histograms showing the number of NeuN-positive (C), DARPP-32–positive (F), and parvalbumin-positive cells (I) in <i>DAT-Ret^lx/lx</i> mutants and age-matched controls (<i>n</i> = 3–5 each genotype). Note also the reduced staining intensities for NeuN and DARPP-32 in <i>DAT-Ret^lx/lx</i> compared to control mice. *, <i>p</i> < 0.05; **, <i>p</i> < 0.01 (Student <i>t</i>-test). Scale bars indicate 50 μm.