Volcano Plots for Temperature, eQTL, and pQTL Effect
- Yang Li (7082)
- Olga Alda Álvarez (274081)
- Evert W Gutteling (274083)
- Marcel Tijsterman (155541)
- Jingyuan Fu (102399)
- Joost A. G Riksen (273895)
- Esther Hazendonk (273897)
- Pjotr Prins (274085)
- Ronald H. A Plasterk (77025)
- Ritsert C Jansen (63185)
- Rainer Breitling (4371)
- Jan E Kammenga (273892)
Publication date
February 2013
DOIAbstract
<div><p>The temperature (T) (A), eQTL (B), and pQTL (C) effects for all genes are plotted on the <i>x</i>-axes.</p><p>(A) Temperature effect −log<sub>10 </sub><i>p</i>-values from intensity-based analysis are plotted on the <i>y</i>-axis.</p><p>(B and C) eQTL and pQTL −log<sub>10 </sub><i>p</i>-values from full model are plotted on the <i>y</i>-axes. Vertical dashed lines correspond to 2-fold change in expression.</p><p>The dotted lines indicate the significance thresholds: (A) FDR 0.01; (B) <i>p</i> = 0.001 for single and two-locus search; (C) <i>p</i> = 0.001 for genomewide (black), single-locus (green), and two-locus (blue) search.</p></div