Linear Correlation of Relative tRNA Abundance to Codon Usage of Tissue-Specific Genes that Are Expressed at High Levels

<div><p>The <i>r</i>- and <i>p</i>-values are indicated in each graph.</p><p>(A) Liver/brain, all data points. Excluding the two outlying data points (circled) gives a linear fit with <i>r</i> = 0.78, <i>p</i> < 0.0001, and a slope of 1.0 ± 0.2. Inclusion of these two data points gives a linear fit with <i>r</i> = 0.62, <i>p</i> = 0.00098, and a slope of 0.8 ± 0.2.</p><p>(B) Three individual isoacceptors across all five tissues show linear correlation with <i>r</i> = 0.90 to 0.94 and <i>p</i> = 0.016 to 0.039.</p><p>(C) Two sets of four tRNA^Arg isoacceptors in liver and thymus show linear correlation with <i>r</i> = 0.93 and 0.97 and <i>p</i> = 0.067 and 0.033, respectively.</p>