<p>Effect of an antioxidant on aggregation. <b>A)</b> Comparison between the intensity-weighted size distributions obtained in the absence and in the presence of DTT. <b>B)</b> Time course of light scattered intensity at 90° angle upon addition of DTT to fresh protein samples. GST, GST-Q22 and GST-Q41 are shown using black, red and green lines, respectively. The measurements shown were carried out at 20°C using 20 µM samples.</p
<p>(n = 200±20 each for data in Fig. 2A to C). A: The proportion of aggregate free cells: Both short...
<p>A) Mouse full-length prion protein (2.6 µM) in 50 mM phosphate buffer was exposed to 290 nm of li...
<p>The initial parts of the dependences of the light scattering intensity on temperature for aggrega...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>Comparison of the intensity-weighted size distribution of GST (black line), GST-Q22 (red line) an...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
NoBiosimilar pharmaceuticals are complex biological molecules that have similar physicochemical prop...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>Effect of temperature on aggregation. <b>A)</b> Light scattered intensity at 90° angle registered...
Protein pharmaceuticals is one of the fastest growing class of therapeutics today. However, they pos...
Monoclonal antibodies and their derivatives have emerged as one of the most successful class of biol...
<p>(A) The dependences of the light scattering intensity (<i>I</i>) on time obtained at the followin...
<p>A) Proteins were dissolved in citrates phosphates McIlvaine’s buffer, pH 5.0 and far-UV circular ...
<p>(n = 200±20 each for data in Fig. 2A to C). A: The proportion of aggregate free cells: Both short...
<p>A) Mouse full-length prion protein (2.6 µM) in 50 mM phosphate buffer was exposed to 290 nm of li...
<p>The initial parts of the dependences of the light scattering intensity on temperature for aggrega...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>Comparison of the intensity-weighted size distribution of GST (black line), GST-Q22 (red line) an...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
NoBiosimilar pharmaceuticals are complex biological molecules that have similar physicochemical prop...
<p>(A) The dependences of the light scattering intensity on time obtained at the following concentra...
<p>Effect of temperature on aggregation. <b>A)</b> Light scattered intensity at 90° angle registered...
Protein pharmaceuticals is one of the fastest growing class of therapeutics today. However, they pos...
Monoclonal antibodies and their derivatives have emerged as one of the most successful class of biol...
<p>(A) The dependences of the light scattering intensity (<i>I</i>) on time obtained at the followin...
<p>A) Proteins were dissolved in citrates phosphates McIlvaine’s buffer, pH 5.0 and far-UV circular ...
<p>(n = 200±20 each for data in Fig. 2A to C). A: The proportion of aggregate free cells: Both short...
<p>A) Mouse full-length prion protein (2.6 µM) in 50 mM phosphate buffer was exposed to 290 nm of li...
<p>The initial parts of the dependences of the light scattering intensity on temperature for aggrega...