An 80% Plaque Reduction Neutralization Titers (PRNT₈₀) for VRP-S and VRP-S+N Hyperimmune Serum

<div><p>(A) Mice vaccinated young: icSARS-CoV (left) and icGDO3-S (right) PRNT₈₀ for VRP-S immune serum (experiment 2) collected at 5 wk post-boost (<i>n</i> = 5) and 53 wk post-boost (<i>n</i> = 8).</p> <p>(B) Mice vaccinated old: icSARS (left) and icGDO3-S (right) PRNT₈₀ values for VRP-S and VRP-S+N immune serum (experiment 4) at 12 and 29 wk post-boost (<i>n</i> = 6 for icSARS; <i>n</i> = 5 for icGDO3-S). The PRNT₈₀ values for individual animals are show as black circles, and the mean value is shown as a solid bar. The limits of detection (1:1,600 upper and 1:100 lower) are represented by horizontal dotted lines.</p>