Over-Representation Analysis of Functional GO Terms for Mc1r- and Kit-Dependent UVB-Responsive Genes in the Basal Epidermis of P2.5 Mice

<p>GO terms, using EASE software [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030009#pgen-0030009-b048" target="_blank">48</a>], were mapped to (A) 120 Mc1r-dependent UVB-responsive genes (red bars) and (B) 147 Kit-dependent UVB-responsive genes (blue bars). GO terms that were significantly enriched (<i>p</i> = 0.05), by 2-fold, relative to all of the assayed genes on the 35,000 array (35,328 genes) (black bars) and that contained at least three gene hits, are displayed. GO terms are ranked, within high level GO branches, by fold-enrichment relative to the 35,000 array. A thumbnail image provides a reference for each of the analyzed UVB response classes.