<p>Results for egg (A) and worm (B) burdens following the experimental protocol depicted in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0040014#pmed-0040014-g001" target="_blank">Figure 1</a> are shown. Points represent data from individual mice which were combined from either two early or two late treatment experiments. The horizontal bars represent median values: **<i>p</i> = 0.002, *** <i>p</i> = 0.0007. The data comparing female worm burdens between late treatment and untreated controls were not statistically different (<i>p</i> = 0.2).</p
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>*Indicates that the 4<sup>th</sup> mouse of this group died prematurely.</p><p>** WBR for clofazi...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
<p>Representative worms treated with K11777 in the experiment outlined in <a href="http://www.plosme...
<p>After necropsy of mice from experiments outlined in <a href="http://www.plosmedicine.org/article/...
<p>(A) male and female worm burdens. (B) egg burden in liver. Infected mice were treated with 500 mg...
<p>Points represent data from individual mice that were infected and treated, infected and untreated...
<p><b>(A)</b> EPIIS effect on worm burden. <b>(B)</b> EPIIS effect on egg development stages (oogram...
<p>Mice harbored a patent <i>S. mansoni</i> infection. Different dosage regimens were used (1×400 mg...
<p>Worm burden (mean +/− SD) in control mice injected with PBS versus mice immunized with r<i>Sm</i>...
<p>Points represent data from individual mice that were infected and treated with EPIIS, or infected...
<p><b>(A)</b> EPIIS effect on egg development stages (oogram) <b>(B)</b> Effect on Stoll egg count. ...
<p>Mice were infected with 60 <i>S</i>. <i>mansoni</i> cercariae through a percutaneous route, and t...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>*Indicates that the 4<sup>th</sup> mouse of this group died prematurely.</p><p>** WBR for clofazi...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
<p>Representative worms treated with K11777 in the experiment outlined in <a href="http://www.plosme...
<p>After necropsy of mice from experiments outlined in <a href="http://www.plosmedicine.org/article/...
<p>(A) male and female worm burdens. (B) egg burden in liver. Infected mice were treated with 500 mg...
<p>Points represent data from individual mice that were infected and treated, infected and untreated...
<p><b>(A)</b> EPIIS effect on worm burden. <b>(B)</b> EPIIS effect on egg development stages (oogram...
<p>Mice harbored a patent <i>S. mansoni</i> infection. Different dosage regimens were used (1×400 mg...
<p>Worm burden (mean +/− SD) in control mice injected with PBS versus mice immunized with r<i>Sm</i>...
<p>Points represent data from individual mice that were infected and treated with EPIIS, or infected...
<p><b>(A)</b> EPIIS effect on egg development stages (oogram) <b>(B)</b> Effect on Stoll egg count. ...
<p>Mice were infected with 60 <i>S</i>. <i>mansoni</i> cercariae through a percutaneous route, and t...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>*Indicates that the 4<sup>th</sup> mouse of this group died prematurely.</p><p>** WBR for clofazi...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...