<p>*Indicates that the 4<sup>th</sup> mouse of this group died prematurely.</p><p>** WBR for clofazimine (200 mg/kg) was calculated based on worm burden of Control Batch 2.</p><p>Worm burden reductions of <i>S</i>.<i>mansoni-</i>infected mice treated with <i>in vitro-</i>hit FDA Pharmakon compounds.</p
<p><b>(A)</b> EPIIS effect on worm burden. <b>(B)</b> EPIIS effect on egg development stages (oogram...
<p>Mice were immunized 1x (a) or 2x (b) with rSG3PDH+PRX-MAP alone or combined with SmCB+FhCL, and c...
<p>Female BALB/c mice (n = 33) were infected with 5 × 10<sup>6</sup><i>L</i>. <i>major</i> promastig...
<p>Mice harbored a patent <i>S. mansoni</i> infection. Different dosage regimens were used (1×400 mg...
<p>(A) male and female worm burdens. (B) egg burden in liver. Infected mice were treated with 500 mg...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
<p>Results for egg (A) and worm (B) burdens following the experimental protocol depicted in <a href=...
<p>These results represent the effect on worm burden of a single 40/kg oral dose of phytol administe...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
This study was designed for assessment of 3 types of Cysteine protease inhibitors (CPIs) fluromethyl...
This study was designed for assessment of 3 types of Cysteine protease inhibitors (CPIs) fluromethyl...
<p>Shown are the intestinal worm burdens after treatment <i>per os</i> with the drugs in comparison ...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Representative worms treated with K11777 in the experiment outlined in <a href="http://www.plosme...
<p><b>(A)</b> EPIIS effect on worm burden. <b>(B)</b> EPIIS effect on egg development stages (oogram...
<p>Mice were immunized 1x (a) or 2x (b) with rSG3PDH+PRX-MAP alone or combined with SmCB+FhCL, and c...
<p>Female BALB/c mice (n = 33) were infected with 5 × 10<sup>6</sup><i>L</i>. <i>major</i> promastig...
<p>Mice harbored a patent <i>S. mansoni</i> infection. Different dosage regimens were used (1×400 mg...
<p>(A) male and female worm burdens. (B) egg burden in liver. Infected mice were treated with 500 mg...
<p>Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy...
<p> = 20 mice were used for each group.<sup>, </sup> p<0.05 (Non-selected vs. Selected). N</p><p><su...
<p>Results for egg (A) and worm (B) burdens following the experimental protocol depicted in <a href=...
<p>These results represent the effect on worm burden of a single 40/kg oral dose of phytol administe...
<p>The histograms show the % of worm burdens in mice treated with DMSO, PZQ and PHX. In white is rep...
This study was designed for assessment of 3 types of Cysteine protease inhibitors (CPIs) fluromethyl...
This study was designed for assessment of 3 types of Cysteine protease inhibitors (CPIs) fluromethyl...
<p>Shown are the intestinal worm burdens after treatment <i>per os</i> with the drugs in comparison ...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Representative worms treated with K11777 in the experiment outlined in <a href="http://www.plosme...
<p><b>(A)</b> EPIIS effect on worm burden. <b>(B)</b> EPIIS effect on egg development stages (oogram...
<p>Mice were immunized 1x (a) or 2x (b) with rSG3PDH+PRX-MAP alone or combined with SmCB+FhCL, and c...
<p>Female BALB/c mice (n = 33) were infected with 5 × 10<sup>6</sup><i>L</i>. <i>major</i> promastig...