a<p>: Counted only the founders where progeny was analyzed by both methods.</p>b<p>: Calculated assuming only one embryo in the pools with mutant peaks is heterozygous.</p
<p>A) Table showing somatic mutation rates of ZFNs and TALENs for five genes. Mutation rate was calc...
<p>(A) TALEN RNA-injected G0 founders transmit targeted mutations to their offspring. G0 founders we...
Background: The number of founding germ cells (FGCs) in mammals is of fundamental significance to th...
<p>The cumulative percentage of embryos that were dead or deformed by 3 days post-fertilization is d...
<p>To detect transmission of germ line mutations, TALEN RNA-injected G0 embryos were raised to adult...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p><b>A</b>. Absolute abundance (in numbers) of the 70R mutation. <b>B</b>. Relative abundance of th...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
Germline mutation rates measured per generation per locus in three species of Metazoa are used to ad...
<p>Ploidy is <i>c</i> = 2<sup><i>n</i></sup> (<i>n</i> ≥ 1) in the polyploid cases, is the per-copy...
<p><b>N:</b> number of progenies displaying haploid profiles of DNA content. <b>2N:</b> number of pr...
<p>Individual female was crossed with wildtype (<i>w<sup>1118</sup></i>) male flies and the number o...
<p>(A–F) Percentage of cells that have completed at least the first meiotic division (post-MI) in in...
<p>*Counts of male self-progeny were corrected based on the expectation that 12.5% of male progeny a...
<p>A) Table showing somatic mutation rates of ZFNs and TALENs for five genes. Mutation rate was calc...
<p>(A) TALEN RNA-injected G0 founders transmit targeted mutations to their offspring. G0 founders we...
Background: The number of founding germ cells (FGCs) in mammals is of fundamental significance to th...
<p>The cumulative percentage of embryos that were dead or deformed by 3 days post-fertilization is d...
<p>To detect transmission of germ line mutations, TALEN RNA-injected G0 embryos were raised to adult...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
<p><b>A</b>. Absolute abundance (in numbers) of the 70R mutation. <b>B</b>. Relative abundance of th...
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mut...
Germline mutation rates measured per generation per locus in three species of Metazoa are used to ad...
<p>Ploidy is <i>c</i> = 2<sup><i>n</i></sup> (<i>n</i> ≥ 1) in the polyploid cases, is the per-copy...
<p><b>N:</b> number of progenies displaying haploid profiles of DNA content. <b>2N:</b> number of pr...
<p>Individual female was crossed with wildtype (<i>w<sup>1118</sup></i>) male flies and the number o...
<p>(A–F) Percentage of cells that have completed at least the first meiotic division (post-MI) in in...
<p>*Counts of male self-progeny were corrected based on the expectation that 12.5% of male progeny a...
<p>A) Table showing somatic mutation rates of ZFNs and TALENs for five genes. Mutation rate was calc...
<p>(A) TALEN RNA-injected G0 founders transmit targeted mutations to their offspring. G0 founders we...
Background: The number of founding germ cells (FGCs) in mammals is of fundamental significance to th...
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