<div><p>Data (red lines), best (blue lines), and worst (green lines) model of our selection are compared for different synaptic responses.</p><p>(A) Complex spike in the soma (left), main dendrite (middle), and smooth dendrite (right) after activation of the climbing fiber at time 0.2 s.</p><p>(B) Simple spike frequency response to different levels of excitation and inhibition.</p><p>(C) EPSPs generated by a synchronous parallel fiber input plus an asynchronous background excitation and inhibition. EPSPs are generated in four different branchlets and recorded at the soma, which is passive. The traces show the average of 40 EPSPs obtained with different random number generator seeds.</p></div
<p>Simulated glutamatergic inputs were activated either on a single dendritic location (focal distri...
<p>All simulations with = 2.5 with increasing numbers of excitatory synapses assuming the average n...
(a) Illustration of the three neuron and nine synapse types considered in this study. (b) Characteri...
A) Average EPSP slope, calculated from the 18 model synapses (red squares, using a Δt = 5 ms) and ex...
<p>A, Examples of the morphologies and the input-output relations in simulated cortical layer 2/3 py...
<p>A,B, The correlation between the number of synapses required for a global NMDA-spike generation i...
<p>(<b>A-D</b>) EPSPs at different locations along a single dendritic branch (branch 3), as a respon...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
<p>Electrotonic attenuation of the synaptic current along the dendrites en route to the soma, result...
<p>(A–C) The left column shows simulation results with synchronicity of 0 ms, middle column of 4 ms,...
A simple mathematical model of synaptic activation shows that the response to synaptic activation de...
<p>Synaptic summation was probed by comparing between the linear summation of somatic responses foll...
A: Waveforms of excitatory post-synaptic conductances (EPSGs) and V2 responses in panels B-D. Inputs...
<p>A: For a synaptically coupled pair of cells (red arrow), presynaptic common neighbors are those c...
(A) Morphology of reconstructed dSPN with cartoon to illustrate the direction of stimulation along a...
<p>Simulated glutamatergic inputs were activated either on a single dendritic location (focal distri...
<p>All simulations with = 2.5 with increasing numbers of excitatory synapses assuming the average n...
(a) Illustration of the three neuron and nine synapse types considered in this study. (b) Characteri...
A) Average EPSP slope, calculated from the 18 model synapses (red squares, using a Δt = 5 ms) and ex...
<p>A, Examples of the morphologies and the input-output relations in simulated cortical layer 2/3 py...
<p>A,B, The correlation between the number of synapses required for a global NMDA-spike generation i...
<p>(<b>A-D</b>) EPSPs at different locations along a single dendritic branch (branch 3), as a respon...
<p>The neuron models and stimulation protocols were the same as those used in <a href="http://www.pl...
<p>Electrotonic attenuation of the synaptic current along the dendrites en route to the soma, result...
<p>(A–C) The left column shows simulation results with synchronicity of 0 ms, middle column of 4 ms,...
A simple mathematical model of synaptic activation shows that the response to synaptic activation de...
<p>Synaptic summation was probed by comparing between the linear summation of somatic responses foll...
A: Waveforms of excitatory post-synaptic conductances (EPSGs) and V2 responses in panels B-D. Inputs...
<p>A: For a synaptically coupled pair of cells (red arrow), presynaptic common neighbors are those c...
(A) Morphology of reconstructed dSPN with cartoon to illustrate the direction of stimulation along a...
<p>Simulated glutamatergic inputs were activated either on a single dendritic location (focal distri...
<p>All simulations with = 2.5 with increasing numbers of excitatory synapses assuming the average n...
(a) Illustration of the three neuron and nine synapse types considered in this study. (b) Characteri...