Syfpeithi and Bimas Predictions for HLA-A*0201

<p>The top two panels contain scatter plots of the predicted binding scores (<i>x</i>-axis) against the measured binding affinities (<i>y</i>-axis) for all 3,089 9-mer peptides binding to HLA-A*0201 in our database. Both bimas and syfpeithi do not predict IC₅₀ values, but have output scales in which high scores indicate good binding candidates. Therefore, the regression curves are inverted. The bottom panel contains an ROC analysis of the same data with the classification cutoff of 500 nM.