An Overview of Dependency of the Direction of Cell Sorting, for Both Single Cells and Small Clusters, on the Specific Combinations of Surface Energies, in a Confined Cell Mass

<p><i>J_l,l</i> is fixed; where the lines I–IV intersect, <i>J_l,l</i> = <i>J_d,l</i> = <i>J_d,d</i>. Line I corresponds to <i>γ</i> = 0 (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020056#pcbi-0020056-e006" target="_blank">Equation 6</a>); line II to <i>J_d,l</i> = <i>J_l,l;</i> line III to <i>J_d,d</i> = <i>J_l,l;</i> and line IV to <i>J_d,d</i> = <i>J_d,l</i>. Arrows indicate the direction of sorting of the dark cell type, when chemotaxis directs cells to the right and movement is constrained. The arrows solely indicate the direction of sorting; quantitative differences between single cells and clusters are not shown. For movies of the cell behaviour in each region, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020056#pcbi-0020056-sv003" target="_blank">Videos S3</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020056#pcbi-0020056-sv008" target="_blank">S8</a>.