Orientation of cell division.

<p>Comparison of predicted (red, from ellipse fitting) and experimental (green, from mitotic spindle) orientations for various micropatterns. The experimental data is for HeLa-cell [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004863#pcbi.1004863.ref014" target="_blank">14</a>]. The histograms show the statistical distributions of the orientation of the cell division axis. In our two-dimensional model, this orientation is given by the polar angle (zero for the x-axis). For each pattern 20.000 cell divisions were simulated, resulting in the observed variability. Model parameters as given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004863#pcbi.1004863.t001" target="_blank">Table 1</a> (generic cell).