<p>E42 pig pancreatic tissue was transplanted into NOD-SCID mice. Grafts were histologically analyzed at 3 (A), 6 (B), 8 (C), and 10 mo (D) after transplant. Endocrine expression is tracked by anti-insulin staining (blue), exocrine expression by anti-trypsin and anti-amylase staining (green), and proliferation status by anti-Ki67 staining (red). Cells coexpressing insulin and Ki67 are marked by arrows (A and B).</p
<p>(A) Upper panel: Macroscopic view at 3 months post transplant of E-42 spleen grafts implanted int...
<p>A–C: Staining for insulin (red), SV40T (green) and DAPI (blue); D–F: Staining for insulin (red), ...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. Kidney ...
<div><p>(A) Pig insulin secretion by E42 pig pancreatic grafts implanted under the kidney capsule of...
<p>Pig insulin levels were measured 4 wk after transplantation of E42 and E56 pig pancreas into NOD-...
<p>Mice were tested 6 wk after transplantation, and pig insulin levels were measured before ( <i>T</...
<p>(A–B) Tissue sections of E14–15.5 pancreatic epithelial grafts transplanted in BM-reconstituted I...
<div><p>(A) Glucose levels in durably grafted (E42 embryonic pancreas) and non-grafted alloxan-treat...
<p>(A) Immunohistochemical staining of pancreatic tissues derived from 8–10 weeks old control C57BL/...
<p>Images show immuno-stainings for insulin (<b>A</b>, <b>B</b>), glucagon (<b>C</b>, <b>D</b>), and...
<p>Double immunofluorescent staining of insulin (green) and glucagon (red) in ICCs transplanted unde...
<p>Human embryonic pancreases were transplanted into <i>scid</i> mice. Ten days and 4.5 months later...
<p>(A) Teratoma/tumorigenic Assay. One Balb/c-nude mouse approximately 1.5 months after grafting is ...
<p>Colocalization of insulin (A; brown) and iron (B; blue) staining in CSPIO-labeled islet grafts. S...
Foetal islets are functionally immature but retain their capacity for proliferation if harvested and...
<p>(A) Upper panel: Macroscopic view at 3 months post transplant of E-42 spleen grafts implanted int...
<p>A–C: Staining for insulin (red), SV40T (green) and DAPI (blue); D–F: Staining for insulin (red), ...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. Kidney ...
<div><p>(A) Pig insulin secretion by E42 pig pancreatic grafts implanted under the kidney capsule of...
<p>Pig insulin levels were measured 4 wk after transplantation of E42 and E56 pig pancreas into NOD-...
<p>Mice were tested 6 wk after transplantation, and pig insulin levels were measured before ( <i>T</...
<p>(A–B) Tissue sections of E14–15.5 pancreatic epithelial grafts transplanted in BM-reconstituted I...
<div><p>(A) Glucose levels in durably grafted (E42 embryonic pancreas) and non-grafted alloxan-treat...
<p>(A) Immunohistochemical staining of pancreatic tissues derived from 8–10 weeks old control C57BL/...
<p>Images show immuno-stainings for insulin (<b>A</b>, <b>B</b>), glucagon (<b>C</b>, <b>D</b>), and...
<p>Double immunofluorescent staining of insulin (green) and glucagon (red) in ICCs transplanted unde...
<p>Human embryonic pancreases were transplanted into <i>scid</i> mice. Ten days and 4.5 months later...
<p>(A) Teratoma/tumorigenic Assay. One Balb/c-nude mouse approximately 1.5 months after grafting is ...
<p>Colocalization of insulin (A; brown) and iron (B; blue) staining in CSPIO-labeled islet grafts. S...
Foetal islets are functionally immature but retain their capacity for proliferation if harvested and...
<p>(A) Upper panel: Macroscopic view at 3 months post transplant of E-42 spleen grafts implanted int...
<p>A–C: Staining for insulin (red), SV40T (green) and DAPI (blue); D–F: Staining for insulin (red), ...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. Kidney ...