High-Resolution Pairwise Substitution Rate Estimates <i>(K)</i> across Promoter Region Alignments

<div><p>The <i>x-</i>axis denotes nucleotide position relative to the TSS reference position at +1 (grey vertical line). Error bars (lighter shading) show 95% confidence intervals for each data point.</p> <p>(A) Rates calculated from mouse-based alignments.</p> <p>(B) Rates calculated from human-based alignments.</p>