Localization of ARS Elements

<div><p>(A) Replication timing profile of Chromosome 3. The two peaks indicated by red stars are predicted with high confidence to contain replication origins. (Data replotted from [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0010007#pcbi-0010007-b23" target="_blank">23</a>].)</p> <p>(B and C) SIDD profiles of the two peak regions (from [A]) are plotted to high resolution, along with locations of the known ARS element (red) and the DNA segments within which ORC and MCM proteins were shown to bind [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0010007#pcbi-0010007-b22" target="_blank">22</a>] (yellow). (B) shows the profile around ARS 310, and (C) shows that of ARS 314.</p>