Modeling of cells exposed to different extracellular media compositions.
- Juan M. Fernández (382010)
- Gisela Di Giusto (382011)
- Maia Kalstein (382012)
- Luciana Melamud (382013)
- Valeria Rivarola (382014)
- Paula Ford (382015)
- Claudia Capurro (382016)
Publication date
February 2013
DOIAbstract
<p>Time courses of V<sub>t</sub>/V<sub>0</sub> (<b>A</b>), V<sub>m</sub>/V<sub>m0</sub> (<b>B</b>), J<sub>net</sub> (<b>C</b>) and V<sub>m</sub>, Eq<sub>Cl</sub>, Eq<sub>K</sub> (<b>D</b>) simulated in cells exposed to either HYPO<sub>NaCl</sub> or to HYPO<sub>Mannitol</sub>. At time = 0 extracellular osmolarity was reduced (ΔOsM = 100 mOsM) and after a delay of 20 s, P<sub>K</sub> and P<sub>Cl</sub> increased according to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057268#pone.0057268.e006" target="_blank">Equation 4</a>. A negative value of <i>J</i><sub>net</sub> indicates an outward flux.</p
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