Average solvent accessible surface area (SASA in Ų)^a of loop LB hydrophobic residues.

a<p>SASA was calculated for a given residue using the g_sas tool available in GROMACS version 3.3 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054397#pone.0054397-vanderSpoel1" target="_blank">[39]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054397#pone.0054397-Lindahl1" target="_blank">[40]</a>.</p>b<p>Residues shown in bold participate in stable interactions with at least one of the BH3 peptide ligands in Bcl-X_L complex simulations <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054397#pone.0054397-Lama1" target="_blank">[30]</a>.</p>c<p>For each residue, the top and bottom numbers represent respectively the average SASA values calculated for the first and the last 5 ns of production runs. If the residues are buried during the simulation, then the values are shown in italics and underlined. SASA values of exposed residues are shown in bold.