Multivariate analysis of cotreatment-related metabolite data.

<p>A- PCA of data related to cotreatment with curcumin and DTX-L. Each score corresponds to an individual measurement and is labeled as in Fig. 5A. F1 and F2, first 2 principal components with the percentage of total variance of data they account for. Cloud contours are displayed for DTX-L, CO-L-24 h, the set of CO-L-48 h and CO-L-72 h, and CO-L-96 h. Arrows, duration of exposure-related trajectory. B- Corresponding loading plot. Metabolite abbreviations, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057971#pone-0057971-t001" target="_blank">Table 1</a>. C- PCA of data related to cotreatment with curcumin and DTX-H. Each score corresponds to an individual measurement and is labeled as in Fig. 5A. F1 and F2, first 2 principal components with the percentage of total variance of data they account for. Cloud contours are displayed for CO-H-24 h, the set of DTX-H, CO-H-48 h and CO-H-72 h, and CO-H-96 h. Grey arrows, duration of exposure-related trajectory. D- Corresponding loading plot. Metabolite abbreviations, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057971#pone-0057971-t001" target="_blank">Table 1</a>.