<p>Three independent measurements were performed (TK2<sup>+/+</sup> n = 3, TK2<sup>−/−</sup> n = 3) and comparisons between the genotypes were made within each measurement. Data presented as per cent activity (mean ± SEM) compared to TK2<sup>+/+</sup>. The P-value for statistical comparison (two-tailed unpaired Student’s t-test) between TK2<sup>+/+</sup> and TK2<sup>−/−</sup> is shown, *p≤0.05.</p
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>The cytochrome C oxidase activity was measured for each skeletal muscle mitochondrial lysate from...
<p>CS: citrate synthase; G: glutamate; M: malate; S: succinate; P: pyruvate; PC: palmitoyl-L-carniti...
<p>WT, wild-type mice; +/m, heterozygous mutator mice; m/m, homozygous mutator mice; Δ, mito-miceΔ. ...
<p>Oxidation rate was determined with straight-chain acyl-CoA substrates. Tissues tested were (A) li...
<p>Values correspond to the mean ± SD (nmol/mg of wet tissue/h) of 3 animals per group. Tissue sampl...
<p>(<b>A</b>) Representative experiment with a crude mitochondrial pellet from striatum. Blue curve ...
<p>a. Amounts of PGC1α mRNA were measured by qRT-PCR and quantitated relative to tubulin in livers o...
<p>Oxidation and phosphorylation rates were recorded simultaneously in liver (n = 4) and muscle (n =...
<p>(<b>A</b>) Respiration rates in the basal leak condition (state 2), ADP-stimulated condition (sta...
<p>After one week of HFru or HFat feeding, the rates of hepatic oxidation of palmitate (<b>A</b>) an...
Fatty acid utilization capacity was tested measuring both CPT system activity (A) and β-oxidation ra...
<p>Oxygen consumption was measured from isolated liver mitochondria of male mice either fed or faste...
<div><p>(A) Oil red O staining of isolated hepatocytes exposed to BSA alone (BSA) or 50 μM oleate co...
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>The cytochrome C oxidase activity was measured for each skeletal muscle mitochondrial lysate from...
<p>CS: citrate synthase; G: glutamate; M: malate; S: succinate; P: pyruvate; PC: palmitoyl-L-carniti...
<p>WT, wild-type mice; +/m, heterozygous mutator mice; m/m, homozygous mutator mice; Δ, mito-miceΔ. ...
<p>Oxidation rate was determined with straight-chain acyl-CoA substrates. Tissues tested were (A) li...
<p>Values correspond to the mean ± SD (nmol/mg of wet tissue/h) of 3 animals per group. Tissue sampl...
<p>(<b>A</b>) Representative experiment with a crude mitochondrial pellet from striatum. Blue curve ...
<p>a. Amounts of PGC1α mRNA were measured by qRT-PCR and quantitated relative to tubulin in livers o...
<p>Oxidation and phosphorylation rates were recorded simultaneously in liver (n = 4) and muscle (n =...
<p>(<b>A</b>) Respiration rates in the basal leak condition (state 2), ADP-stimulated condition (sta...
<p>After one week of HFru or HFat feeding, the rates of hepatic oxidation of palmitate (<b>A</b>) an...
Fatty acid utilization capacity was tested measuring both CPT system activity (A) and β-oxidation ra...
<p>Oxygen consumption was measured from isolated liver mitochondria of male mice either fed or faste...
<div><p>(A) Oil red O staining of isolated hepatocytes exposed to BSA alone (BSA) or 50 μM oleate co...
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>(A) Steady-state levels of mitochondrial glucose and fatty acid transporters: insulin-regulated g...
<p>The cytochrome C oxidase activity was measured for each skeletal muscle mitochondrial lysate from...