<p>A) RT-qPCR measurements of <i>ftn-1</i> mRNA under normal iron conditions in indicated genetic backgrounds, relative to levels in wild-type animals. B) RT-qPCR measurements of <i>ftn-1</i> mRNA levels in wild-type animals and <i>hlh-29</i> mutants subjected to <i>hif-1</i> RNAi. C) RT-qPCR measurements of <i>ftn-1</i> mRNA in wild-type animals and <i>hlh-29</i> mutants after treatment with BP or FAC. D) RT-qPCR measurements of <i>hlh-29</i> mRNA levels in wild-type animals after treatment with BP or FAC. E) Expression of an integrated transgenic reporter of <i>ftn-1</i> activity in young adult wild-type animals and <i>hlh-29</i> mutants. In panels A - D, error bars represent standard error of the mean (SEM), wild-type = black bars; <i>hl...
<p>Relative expression measured with RNA-Seq and RT-qPCR for 6 genes including 3 glutathione S-trans...
<p>(A) Effect of loss of <i>daf-2</i> and <i>daf-16</i> function on <i>ftn-1</i> mRNA levels. Animal...
Results are shown as target gene mRNA levels normalized to Gapdh mRNA levels. Data are as the mean ±...
<p>A) The lifespans of wild-type animals and <i>hlh-29</i> mutants are similarly affected by 24 mM F...
<p>(A) Expression of <i>Pftn-1::gfp</i> in wild-type and <i>vhl-1(ok161)</i> animals with or without...
<p>The line predicts a 1:1 correspondence (R<sup>2</sup> = 0.750, P<0.0001). The graph includes expr...
<p>(A) RNA blot assays of small RNAs in wild type and <i>henn-1</i> mutant embryos and adults. For e...
<p>A) <i>hlh-29</i> mutants show increased resistance to 10 mM t-BOOH when compared to wild-type ani...
<p>Relative expression levels of genes involved in the regulation of iron metabolism were measured b...
<p>(A) Effect of RNAi of <i>hif-1</i> and <i>aha-1</i> on the expression of <i>Pftn-1::gfp</i>. This...
<p>(A) Effect <i>vhl-1(ok161)</i> on <i>Pftn-1::gfp</i> expression. Experiment was carried out at 20...
<p><i>Bmp6</i> (<b>A, C, E</b>) and <i>Tfr1</i> (<b>B, D, F</b>) mRNA expression was evaluated by qR...
<p><i>Bmp6</i> (<b>A, C, E</b>) and <i>Tfr1</i> (<b>B, D, F</b>) mRNA expression was evaluated by qR...
<p>A) <i>henn-1(tm4477)</i> mutant animals exhibit mildly enhanced somatic RNAi. Animals of the indi...
<p>Relative expression levels of genes involved in the binding and transport of iron were measured b...
<p>Relative expression measured with RNA-Seq and RT-qPCR for 6 genes including 3 glutathione S-trans...
<p>(A) Effect of loss of <i>daf-2</i> and <i>daf-16</i> function on <i>ftn-1</i> mRNA levels. Animal...
Results are shown as target gene mRNA levels normalized to Gapdh mRNA levels. Data are as the mean ±...
<p>A) The lifespans of wild-type animals and <i>hlh-29</i> mutants are similarly affected by 24 mM F...
<p>(A) Expression of <i>Pftn-1::gfp</i> in wild-type and <i>vhl-1(ok161)</i> animals with or without...
<p>The line predicts a 1:1 correspondence (R<sup>2</sup> = 0.750, P<0.0001). The graph includes expr...
<p>(A) RNA blot assays of small RNAs in wild type and <i>henn-1</i> mutant embryos and adults. For e...
<p>A) <i>hlh-29</i> mutants show increased resistance to 10 mM t-BOOH when compared to wild-type ani...
<p>Relative expression levels of genes involved in the regulation of iron metabolism were measured b...
<p>(A) Effect of RNAi of <i>hif-1</i> and <i>aha-1</i> on the expression of <i>Pftn-1::gfp</i>. This...
<p>(A) Effect <i>vhl-1(ok161)</i> on <i>Pftn-1::gfp</i> expression. Experiment was carried out at 20...
<p><i>Bmp6</i> (<b>A, C, E</b>) and <i>Tfr1</i> (<b>B, D, F</b>) mRNA expression was evaluated by qR...
<p><i>Bmp6</i> (<b>A, C, E</b>) and <i>Tfr1</i> (<b>B, D, F</b>) mRNA expression was evaluated by qR...
<p>A) <i>henn-1(tm4477)</i> mutant animals exhibit mildly enhanced somatic RNAi. Animals of the indi...
<p>Relative expression levels of genes involved in the binding and transport of iron were measured b...
<p>Relative expression measured with RNA-Seq and RT-qPCR for 6 genes including 3 glutathione S-trans...
<p>(A) Effect of loss of <i>daf-2</i> and <i>daf-16</i> function on <i>ftn-1</i> mRNA levels. Animal...
Results are shown as target gene mRNA levels normalized to Gapdh mRNA levels. Data are as the mean ±...