<p>Plots of HOMO and LUMO of most active compound 1 along with potent hits KM09155, HTS00581, HTS05891 and Compound1192.</p
<p>Plots of concentration field <i>ϕ</i>(<i>ζ</i>) for strength of heterogeneous reaction <i>K</i><s...
<p>(A) Plot of z-scores for each of the 2240 compounds subjected to the primary screen for ISRE acti...
<p>Top-ranked compounds (hits) with high confidence antiproliferative activity in MTT PHEO cells.</p
<p>Histogram distributions of cLogP, MW and TPSA for (a) the whole HTS set (42,444 compounds, red), ...
<p>Most active non-cyclic urea derivative (141W94) mapped onto: (A) hypothesis 1(four feature mappin...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>LUMO mapped onto a bond surface for studied compounds: a. furoxans, b. benzofuroxans. Blue areas ...
<p>(A) Concentration-response curves and (B) chemical structures of top four compounds with greatest...
<p>List of top hits from the HTS using AlphaLISA and their predicted physico-chemical characteristic...
<p>Distribution plots of several physico-chemical properties of the set of 78 hH<sub>4</sub>R antago...
<p><b>A.</b> VLS dot plot of score values <i>vs</i> molecular volume. Compounds acting as ligands fr...
<p>(a) Plot of LLE vs LE, color coded based on MPO score (min = 1.1, Red; max = 5.75, Green). (b) pl...
<p>Comparison of IC<sub>50</sub>s for compounds inhibiting cAMP generation via Hs.5HT7R (abscissa) o...
Compound activity data sets for the 15 biological targets are deposited, along with structure-activi...
QSAR study has been carried out on the MMP-13 inhibitory activity of fused pyrimidine derivatives po...
<p>Plots of concentration field <i>ϕ</i>(<i>ζ</i>) for strength of heterogeneous reaction <i>K</i><s...
<p>(A) Plot of z-scores for each of the 2240 compounds subjected to the primary screen for ISRE acti...
<p>Top-ranked compounds (hits) with high confidence antiproliferative activity in MTT PHEO cells.</p
<p>Histogram distributions of cLogP, MW and TPSA for (a) the whole HTS set (42,444 compounds, red), ...
<p>Most active non-cyclic urea derivative (141W94) mapped onto: (A) hypothesis 1(four feature mappin...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>LUMO mapped onto a bond surface for studied compounds: a. furoxans, b. benzofuroxans. Blue areas ...
<p>(A) Concentration-response curves and (B) chemical structures of top four compounds with greatest...
<p>List of top hits from the HTS using AlphaLISA and their predicted physico-chemical characteristic...
<p>Distribution plots of several physico-chemical properties of the set of 78 hH<sub>4</sub>R antago...
<p><b>A.</b> VLS dot plot of score values <i>vs</i> molecular volume. Compounds acting as ligands fr...
<p>(a) Plot of LLE vs LE, color coded based on MPO score (min = 1.1, Red; max = 5.75, Green). (b) pl...
<p>Comparison of IC<sub>50</sub>s for compounds inhibiting cAMP generation via Hs.5HT7R (abscissa) o...
Compound activity data sets for the 15 biological targets are deposited, along with structure-activi...
QSAR study has been carried out on the MMP-13 inhibitory activity of fused pyrimidine derivatives po...
<p>Plots of concentration field <i>ϕ</i>(<i>ζ</i>) for strength of heterogeneous reaction <i>K</i><s...
<p>(A) Plot of z-scores for each of the 2240 compounds subjected to the primary screen for ISRE acti...
<p>Top-ranked compounds (hits) with high confidence antiproliferative activity in MTT PHEO cells.</p
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