<p>Distribution plots of several physico-chemical properties of the set of 78 hH<sub>4</sub>R antagonists: Molecular weight distribution (A), Total charge (B), Log P values (C), Number of aromatic atoms (D), number of nitrogen atoms (E), Number of H-bond donors [lip_don] (F), Number of H-bond acceptors [lip_acc] (G).</p
<p>Distribution of nitrogen-containing aromatic heterocyclic pharmacophores among 185 positive hits ...
The data obtained in the earlier parts of this series for the donor and acceptor end parameters of N...
<p>The probability density distributions of relative potency (REP) for the detected phthalate esters...
<p>(a) shows the range of molecular weight of the odorants. Most of the odorants have a molecular we...
<p>P, pos Ionizable, H, hydrophobic; A, H-bond acceptor; R, ring aromatic.</p><p>Scores of common fe...
The prediction of hydrogen-bond (H-bond) acceptor ability is crucial in drug design. This important ...
a<p>Library; <i><sup>b</sup></i>Number of tautomers; <i><sup>c</sup></i>Molecular weight; <i><sup>d<...
The experimental pK(HB) hydrogen-bond (HB) basicity scale and the corresponding Delta H-HB(circle mi...
ABSTRACT: Hydrogen bonding plays an important role in the interaction of biological molecules and th...
As part of our endeavor to enhance survival of natural product derived drug candidates and to guide ...
<p>The distributions estimated for non-halogenated (LH), fluorinated (LF) and other halogenated liga...
<p>The y-axis represents the percentage of compounds, the x-axis represents the molecular weights (M...
<p>(a) Inhibitor 1 (most active), and (<b>b</b>) inhibitor 25 (inactive). Hydrogen bond acceptor fav...
<p>The identification of lead compounds usually includes a step of chemical diversity generation. It...
<p>The pharmacophore features are colored with green, as are the hydrogen-bond acceptors (HBA1, HBA2...
<p>Distribution of nitrogen-containing aromatic heterocyclic pharmacophores among 185 positive hits ...
The data obtained in the earlier parts of this series for the donor and acceptor end parameters of N...
<p>The probability density distributions of relative potency (REP) for the detected phthalate esters...
<p>(a) shows the range of molecular weight of the odorants. Most of the odorants have a molecular we...
<p>P, pos Ionizable, H, hydrophobic; A, H-bond acceptor; R, ring aromatic.</p><p>Scores of common fe...
The prediction of hydrogen-bond (H-bond) acceptor ability is crucial in drug design. This important ...
a<p>Library; <i><sup>b</sup></i>Number of tautomers; <i><sup>c</sup></i>Molecular weight; <i><sup>d<...
The experimental pK(HB) hydrogen-bond (HB) basicity scale and the corresponding Delta H-HB(circle mi...
ABSTRACT: Hydrogen bonding plays an important role in the interaction of biological molecules and th...
As part of our endeavor to enhance survival of natural product derived drug candidates and to guide ...
<p>The distributions estimated for non-halogenated (LH), fluorinated (LF) and other halogenated liga...
<p>The y-axis represents the percentage of compounds, the x-axis represents the molecular weights (M...
<p>(a) Inhibitor 1 (most active), and (<b>b</b>) inhibitor 25 (inactive). Hydrogen bond acceptor fav...
<p>The identification of lead compounds usually includes a step of chemical diversity generation. It...
<p>The pharmacophore features are colored with green, as are the hydrogen-bond acceptors (HBA1, HBA2...
<p>Distribution of nitrogen-containing aromatic heterocyclic pharmacophores among 185 positive hits ...
The data obtained in the earlier parts of this series for the donor and acceptor end parameters of N...
<p>The probability density distributions of relative potency (REP) for the detected phthalate esters...