Supervised clustering showing all differentially expressed (DE) genes.

<p>Microarray comparison of RNA expression from primary E12.5 MGE Lhx6-GFP⁺ cells, ES-Lhx6-GFP⁺ and ES-Lhx6-GFP⁻ cells. Heatmap includes 1821 probes that exhibit a fold change (FC) of greater than 4 in any one of the possible 3 pairwise comparisons. Heatmap colors correspond to the signal intensity relative to the global average for that probe. Color spectrum ranges from red (5) to black (0) to green (-4): red blocks represent sample-specific expression that is elevated relative to the average across all samples; green blocks represent genes whose transcripts are relatively less abundant. Two areas (A and B, bracketed on the right side) in the supervised heatmap contain many of the genes that regulate and/or mark developing cortical interneurons (see Tables S2 and S3 in File S2).