<p>(<b>A</b>) TTC staining for evaluation of infarct volume at day three (left panel) and (<b>B</b>) neurological scores at days one and three (right panel) of wt and <i>Ns<sup>−/−</sup></i> mice after MCAO. Data are represented as means±SD of 10 wt and eight <i>Ns<sup>−/−</sup></i> animals. <i>t</i> test was used to assess statistical significance for infarct sizes and Mann-Whitney U test for neurological scores. (<b>C</b>) Survival rate of wt (n = 13) and <i>Ns<sup>−/−</sup></i> mice (n = 13). Survival was analyzed by the <i>χ</i><sup>2</sup> test (survival rate). (<b>D</b>) In all mice subjected to MCAO, regional cerebral blood flow (rCBF) was measured with Laser Doppler. The decrease in rCBF of approximately 90% was similar between <i>N...
<p><b>A.</b> Representative images of TTC-stained brain sections in mice subjected to 45 min MCAO wi...
Tissue plasminogen activator (tPA) has been implicated in neurite outgrowth and neurological recover...
Summary: Neurotrophins play a protective role during cere-bral ischemia, and mice lacking both allel...
<div><p>The only approved pharmacological treatment for ischemic stroke is intravenous administratio...
The only approved pharmacological treatment for ischemic stroke is intravenous administration of pla...
The only approved pharmacological treatment for ischemic stroke is intravenous administration of pla...
<p>(<b>A</b> and <b>B</b>) Relative expression of <i>Il1b</i>, <i>Tnfa</i>, and <i>Il10</i> mRNAs in...
Background and aims: Critical illness polyneuropathy (CIP) is a common complication of severe system...
<p>A. <i>Myd88<sup>−/−</sup></i> mice have a significantly larger volume of infarct than their WT co...
<p>(<b>A</b>) Absolute numbers of neutrophils (N), macrophages (Mφ), dendritic cells (DC) and lympho...
<p>(A) representative 2,3,5-TTC stained brain slices. The white scale bar corresponds to 1 cm (upper...
<p>(<b>A</b>) Frequency of TNF-α positive brain microglia in wt and <i>Ns<sup>−/−</sup></i> mice ana...
<p>(<b>A</b>) Micrographs showing cresyl violet-stained brain specimens from wild-type mice and TFF3...
Objective: Critical illness polyneuropathy (CIP) is a common complication of severe systemic illness...
Inflammatory processes have been implicated in the pathogenesis of brain damage after stroke. In rod...
<p><b>A.</b> Representative images of TTC-stained brain sections in mice subjected to 45 min MCAO wi...
Tissue plasminogen activator (tPA) has been implicated in neurite outgrowth and neurological recover...
Summary: Neurotrophins play a protective role during cere-bral ischemia, and mice lacking both allel...
<div><p>The only approved pharmacological treatment for ischemic stroke is intravenous administratio...
The only approved pharmacological treatment for ischemic stroke is intravenous administration of pla...
The only approved pharmacological treatment for ischemic stroke is intravenous administration of pla...
<p>(<b>A</b> and <b>B</b>) Relative expression of <i>Il1b</i>, <i>Tnfa</i>, and <i>Il10</i> mRNAs in...
Background and aims: Critical illness polyneuropathy (CIP) is a common complication of severe system...
<p>A. <i>Myd88<sup>−/−</sup></i> mice have a significantly larger volume of infarct than their WT co...
<p>(<b>A</b>) Absolute numbers of neutrophils (N), macrophages (Mφ), dendritic cells (DC) and lympho...
<p>(A) representative 2,3,5-TTC stained brain slices. The white scale bar corresponds to 1 cm (upper...
<p>(<b>A</b>) Frequency of TNF-α positive brain microglia in wt and <i>Ns<sup>−/−</sup></i> mice ana...
<p>(<b>A</b>) Micrographs showing cresyl violet-stained brain specimens from wild-type mice and TFF3...
Objective: Critical illness polyneuropathy (CIP) is a common complication of severe systemic illness...
Inflammatory processes have been implicated in the pathogenesis of brain damage after stroke. In rod...
<p><b>A.</b> Representative images of TTC-stained brain sections in mice subjected to 45 min MCAO wi...
Tissue plasminogen activator (tPA) has been implicated in neurite outgrowth and neurological recover...
Summary: Neurotrophins play a protective role during cere-bral ischemia, and mice lacking both allel...