Comparison of relative lifespan, biomass and viability in the four yeast strains (WT, <i>sch9</i>Δ, <i>tor1</i>Δ, and <i>sir2</i>Δ).

<p>AUC represents the survival integral for lifespan comparison, the AUC of yeast aging in The SD medium is defined as 100%, and error bars represent SEM within 16 replicates. Biomass production was measured as the average values at OD660 of each media from day 10 to day 22 (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064448#pone.0064448.s002" target="_blank"><b>Figure </b><b>S2</b></a>), the biomass of The SD medium was defined as 100%, (mean + SEM, n = 16). Viability was the survival at day 2, and the survival of SD at day 2 was defined as 100%, (mean + SEM, n = 16).