<p>Fluorescent intensity in [Ca2+]i was recorded by laser scanning confocal microscope in different treatment. (A) Representative images of cardiomyocytes. (B and C) Bar graph of fluorescent intensity. All data were expressed as mean±SEM (<i>n</i> = 6). *<i>P</i><0.05 compared with control group; @<i>P</i><0.05 compared with model group; #<i>P</i><0.05 compared with model+GdCl3 group; &<i>P</i><0.05 compared with control group. Groups in B were control, model, model+GdCl3, model+NPS-2390+GdCl3, model+NPS-2390, and control+GdCl3. Groups in C were control, model, model+GdCl3, siRNA+model+GdCl3, nRNA+model, and siRNA+model. Glucose: 25.5 mM; GdCl3: 300 µM; NPS-2390: 10 µM.</p
<p>A/Image of fluo5F calcium-dependent fluorescence after addition of 2 nM EGF. ROIs were drawn over...
Studies in isolated cardiomyocytes have provided tremendous information at the cellular and molecula...
<p>Comparison of the effects of IGF-1 stimulation on cytoplasmic and nuclear Ca<sup>2+</sup> levels ...
<p>(A) Thirty fluorescence images of single cardiomyocyte were scanned at the interval of 10 s. 0, 8...
<p>(<b>A</b>) Bright TUNEL-positive images from control, H<sub>2</sub>O<sub>2</sub> treated and H<su...
<p>A) An example trace of Ca<sup>2+</sup> transients using the Fura-2 fluorescent dye. The cell was ...
Calcium (Ca2+) is a key player in cardiomyocyte homeostasis, and its roles span from excitation-cont...
(A) Representative calcium transients. The fluorescence ratio (410/490 nm) of indo-1 is plotted alon...
Although defective calcium (Ca2+) regulation has been marked as the cardinal cause of heart failure ...
<p>A: Resting intracellular Ca<sup>2+</sup> fluorescence intensity; B: R...
<p>Ca<sup>2+</sup> transients were evoked by application of 10 µM forskolin alone (n = 3) or in addi...
<p>Graphical representation of the calcium transient in a beating CPS cell–derived cardiomyocyte (A)...
Intracellular calcium ion ([Ca2+]i) transients were measured in single rat ventricular myocytes with...
(A) A whole-cell Ca2+ fluorescence tracing showing the experimental protocol with 0.5, 4 and 8 Hz pa...
<p>(A) Representative recordings for increase in [Ca<sup>2+</sup>]i transient amplitude and frequenc...
<p>A/Image of fluo5F calcium-dependent fluorescence after addition of 2 nM EGF. ROIs were drawn over...
Studies in isolated cardiomyocytes have provided tremendous information at the cellular and molecula...
<p>Comparison of the effects of IGF-1 stimulation on cytoplasmic and nuclear Ca<sup>2+</sup> levels ...
<p>(A) Thirty fluorescence images of single cardiomyocyte were scanned at the interval of 10 s. 0, 8...
<p>(<b>A</b>) Bright TUNEL-positive images from control, H<sub>2</sub>O<sub>2</sub> treated and H<su...
<p>A) An example trace of Ca<sup>2+</sup> transients using the Fura-2 fluorescent dye. The cell was ...
Calcium (Ca2+) is a key player in cardiomyocyte homeostasis, and its roles span from excitation-cont...
(A) Representative calcium transients. The fluorescence ratio (410/490 nm) of indo-1 is plotted alon...
Although defective calcium (Ca2+) regulation has been marked as the cardinal cause of heart failure ...
<p>A: Resting intracellular Ca<sup>2+</sup> fluorescence intensity; B: R...
<p>Ca<sup>2+</sup> transients were evoked by application of 10 µM forskolin alone (n = 3) or in addi...
<p>Graphical representation of the calcium transient in a beating CPS cell–derived cardiomyocyte (A)...
Intracellular calcium ion ([Ca2+]i) transients were measured in single rat ventricular myocytes with...
(A) A whole-cell Ca2+ fluorescence tracing showing the experimental protocol with 0.5, 4 and 8 Hz pa...
<p>(A) Representative recordings for increase in [Ca<sup>2+</sup>]i transient amplitude and frequenc...
<p>A/Image of fluo5F calcium-dependent fluorescence after addition of 2 nM EGF. ROIs were drawn over...
Studies in isolated cardiomyocytes have provided tremendous information at the cellular and molecula...
<p>Comparison of the effects of IGF-1 stimulation on cytoplasmic and nuclear Ca<sup>2+</sup> levels ...