Representative CPMG ¹H NMR spectra of serum obtained from (A) controls and (B) COPD patients.

<p>The region of δ 6.5–9.0 (in the dashed box) was magnified 16 times compared with corresponding region of δ 0.5–5.5 for the purpose of clarity. Keys: 1-MH: 1-Methylhistidine; 3-MH: 3-Methylhistidine; AA: Acetoacetate; Ace: Acetate; Act: Acetone; Ala: Alanine; Cr: Creatine; Eth: Ethanol; For: Formate; Glc: Glucose; Gln: Glutamine; Glu: Glutamate; Gly: Glycine; GPC: Glycerolphosphocholine; Ileu: Isoleucine; L1: HDL, CH3-(CH2)n-; L2: VLDL, CH3-(CH2)n-; L3: HDL, CH3-(CH2)n-; L4: VLDL, CH3-(CH2)n-; L5: VLDL, -CH2-CH2-C = O; L6: Lipid, -CH2-CH = CH-; L7: Lipid, -CH2-CH = CH-; L8: Lipid, -CH2-C = O; L9: Lipid, = CH-CH2-CH = ; L10: Lipid, -CH = CH-; Lac: Lactate; Leu: Leucine; Lys: Lysine; m-I: myo-Inositol; NAG: N-acetyl glycoprotein signals; Phe: Phenylalanine; Tyr: Tyrosine; Val: Valine.